[HTML][HTML] The interplay between mineral metabolism, vascular calcification and inflammation in Chronic Kidney Disease (CKD): challenging old concepts with new facts

C Viegas, N Araújo, C Marreiros, D Simes - Aging (Albany NY), 2019 - ncbi.nlm.nih.gov
Chronic kidney disease (CKD) is one of the most powerful predictors of premature
cardiovascular disease (CVD), with heightened susceptibility to vascular intimal and medial …

Targeting vascular calcification in chronic kidney disease

AJ Nelson, P Raggi, M Wolf, AM Gold… - Basic to Translational …, 2020 - jacc.org
Cardiovascular (CV) disease remains an important cause of morbidity and mortality for
patients with chronic kidney disease (CKD). Although clustering of traditional risk factors with …

Con: vascular calcification is a surrogate marker, but not the cause of ongoing vascular disease, and it is not a treatment target in chronic kidney disease

C Zoccali, G London - Nephrology Dialysis Transplantation, 2015 - academic.oup.com
In this narrative review, we discuss the dynamics and pathobiology of calcium accumulation
in the arterial system and then appraise the validity of vascular calcification as a surrogate …

Arterial calcification in chronic kidney disease: key roles for calcium and phosphate

CM Shanahan, MH Crouthamel, A Kapustin… - Circulation …, 2011 - Am Heart Assoc
Vascular calcification contributes to the high risk of cardiovascular mortality in chronic kidney
disease (CKD) patients. Dysregulation of calcium (Ca) and phosphate (P) metabolism is …

Mechanistic insights into CKD-MBD-related vascular calcification and its clinical implications

R Kaur, R Singh - Life Sciences, 2022 - Elsevier
Abstract Chronic Kidney Disease (CKD) is linked to a rising prevalence of morbidity and
mortality primarily from cardiovascular complications and is considered a high or very high …

[HTML][HTML] Vascular calcification in chronic kidney disease: diversity in the vessel wall

P Dube, A DeRiso, M Patel, D Battepati… - Biomedicines, 2021 - mdpi.com
Vascular calcification (VC) is one of the major causes of cardiovascular morbidity and
mortality in patients with chronic kidney disease (CKD). VC is a complex process expressing …

[HTML][HTML] Vascular calcification in chronic kidney disease: an update and perspective

SC Ren, N Mao, S Yi, X Ma, JQ Zou, X Tang… - Aging and …, 2022 - ncbi.nlm.nih.gov
Chronic kidney disease is a devastating condition resulting from irreversible loss of nephron
numbers and function and leading to end-stage renal disease and mineral disorders …

[HTML][HTML] Clinical approach to vascular calcification in patients with non-dialysis dependent chronic kidney disease: mineral-bone disorder-related aspects

J Bover, A Aguilar, C Arana, P Molina, MJ Lloret… - Frontiers in …, 2021 - frontiersin.org
Chronic kidney disease (CKD) is associated with a very high morbimortality, mainly from
cardiovascular origin, and CKD is currently considered in the high-or very high risk …

Updates on the mechanisms and the care of cardiovascular calcification in chronic kidney disease

L Hénaut, JM Chillon, S Kamel, ZA Massy - Seminars in nephrology, 2018 - Elsevier
In chronic kidney disease (CKD), the progressive decrease in renal function leads to
disturbances of mineral metabolism that generally cause secondary hyperparathyroidism …

Vascular calcification: an important understanding in nephrology

S Zununi Vahed, S Mostafavi… - Vascular Health and …, 2020 - Taylor & Francis
Vascular calcification (VC) is a life-threatening state in chronic kidney disease (CKD). High
cardiovascular mortality and morbidity of CKD cases may root from medial VC promoted by …