Redox potentials of glutaredoxins and other thiol-disulfide oxidoreductases of the thioredoxin superfamily determined by direct protein-protein redox equilibria
F Åslund, KD Berndt, A Holmgren - Journal of Biological Chemistry, 1997 - ASBMB
Glutaredoxins belong to the thioredoxin superfamily of structurally similar thiol-disulfide
oxidoreductases catalyzing thiol-disulfide exchange reactions via reversible oxidation of two …
oxidoreductases catalyzing thiol-disulfide exchange reactions via reversible oxidation of two …
Expression pattern of human glutaredoxin 2 isoforms: identification and characterization of two testis/cancer cell-specific isoforms
ME Lönn, C Hudemann, C Berndt… - Antioxidants & redox …, 2008 - liebertpub.com
The cellular redox state is associated with major cellular processes including differentiation,
transformation, and apoptosis. Glutaredoxin 2 (Grx2) is a mitochondrial oxidoreductase …
transformation, and apoptosis. Glutaredoxin 2 (Grx2) is a mitochondrial oxidoreductase …
The yeast iron regulatory proteins Grx3/4 and Fra2 form heterodimeric complexes containing a [2Fe-2S] cluster with cysteinyl and histidyl ligation
The transcription of iron uptake and storage genes in Saccharomyces cerevisiae is primarily
regulated by the transcription factor Aft1. Nucleocytoplasmic shuttling of Aft1 is dependent …
regulated by the transcription factor Aft1. Nucleocytoplasmic shuttling of Aft1 is dependent …
Human mitochondrial glutaredoxin reduces S-glutathionylated proteins with high affinity accepting electrons from either glutathione or thioredoxin reductase
Glutaredoxins catalyze glutathione-dependent thiol disulfide oxidoreductions via a GSH-
binding site and active cysteines. Recently a second human glutaredoxin (Grx2), which is …
binding site and active cysteines. Recently a second human glutaredoxin (Grx2), which is …
Histidine 103 in Fra2 is an iron-sulfur cluster ligand in the [2Fe-2S] Fra2-Grx3 complex and is required for in vivo iron signaling in yeast
The BolA homologue Fra2 and the cytosolic monothiol glutaredoxins Grx3 and Grx4
together play a key role in regulating iron homeostasis in Saccharomyces cerevisiae …
together play a key role in regulating iron homeostasis in Saccharomyces cerevisiae …
Role of glutaredoxin-1 and glutathionylation in cardiovascular diseases
Cardiovascular diseases are the leading cause of death worldwide, and as rates continue to
increase, discovering mechanisms and therapeutic targets become increasingly important …
increase, discovering mechanisms and therapeutic targets become increasingly important …
Thioredoxins, glutaredoxins, and glutathionylation: new crosstalks to explore
L Michelet, M Zaffagnini, V Massot, E Keryer… - Photosynthesis …, 2006 - Springer
Oxidants are widely considered as toxic molecules that cells have to scavenge and detoxify
efficiently and continuously. However, emerging evidence suggests that these oxidants can …
efficiently and continuously. However, emerging evidence suggests that these oxidants can …
Glutathione-thiyl radical scavenging and transferase properties of human glutaredoxin (thioltransferase): potential role in redox signal transduction
DW Starke, PB Chock, JJ Mieyal - Journal of Biological Chemistry, 2003 - ASBMB
Glutaredoxin (GRx, thioltransferase) is implicated in cellular redox regulation, and it is
known for specific and efficient catalysis of reduction of protein-SS-glutathione-mixed …
known for specific and efficient catalysis of reduction of protein-SS-glutathione-mixed …
Redox control and oxidative stress in yeast cells
E Herrero, J Ros, G Bellí, E Cabiscol - Biochimica et Biophysica Acta (BBA) …, 2008 - Elsevier
Protein structure and function can be altered by reactive oxygen species produced either by
cell metabolism or by external oxidants. Although catalases, superoxide dismutases and …
cell metabolism or by external oxidants. Although catalases, superoxide dismutases and …
Plant thioredoxins and glutaredoxins: identity and putative roles
Y Meyer, L Verdoucq, F Vignols - Trends in plant science, 1999 - cell.com
Thioredoxins and glutaredoxins are ubiquitous proteins that reduce disulphide bridges of
oxidized target proteins in vitro. In contrast to the situations in other organisms, phylogenic …
oxidized target proteins in vitro. In contrast to the situations in other organisms, phylogenic …