Chemokine receptors and their chemokine ligands, key mediators of inflammatory and
immune cell trafficking, are involved in the regulation of both physiological and pathological …

Chronic obstructive pulmonary disease (COPD) is a debilitating disease characterized by
recurrent episodes of leukocyte infiltration in the lung parenchyma causing progressive …

Many disease states within the airway result in the co-ordinated infiltration of key
inflammatory cells. The cellular influx is choreographed through the temporal and spatially …

Chemokines and their receptors play important roles in the pathophysiology of many
diseases by regulating the cellular migration of major inflammatory and immune players …

Recruitment of inflammatory cells into the airways is a critical event that triggers and sustains
the clinical manifestations of asthma and chronic obstructive pulmonary disease. Since the …

Selective leukocyte trafficking and recruitment is primarily regulated by a specific family of
small proteins called “chemokines”. This extended family shepherds and guides leukocytes …

Chronic obstructive pulmonary disease (COPD) is an increasing global health problem for
which there are no effective disease-modifying therapies. COPD involves chronic …

Chronic obstructive pulmonary disease (COPD) is one of the leading causes of mortality and
disability in the world, with a prevalence that is expected to increase in the next decades …

The incidence of asthma has continued to rise worldwide with the number of severe
asthmatic episodes dramatically increasing especially in children. Over the past several …

Chronic obstructive pulmonary disease (COPD) is characterised by an abnormal
inflammatory response of the lung to noxious particles or gases. The cellular inflammatory …