Background: One of the major concerns is a nephropathy in diabetes, which applies many
different kinds of medicines. However, required level of the treatment of renal disease has …

Hypothesis: This study aimed to elucidate the role of glibenclamide in the prevention of
diabetic nephropathy and to compare it with a reference drug captopril in rats. Materials and …

Hyperglycemia, hypertension, dyslipidemia, and inflammation have been proposed to
account for the development of nephropathy in diabetic subjects. The beneficial effects of …

Background: Diabetic nephropathy (DN) is one of the most common causes of end-stage
renal failure. The pathogenesis of progressive renal damage is multifactorial and the …

Aims: It was reported that exenatide ameliorated renal injury in diabetic rats. The present
study was carried out to evaluate the effect of exenatide on 24-hour urinary albumin, urinary …

Aims Diabetic nephropathy, a major threat to diabetic patients, is considered as the main
reason for end-stage renal disease. Fortunately, incretin-based therapy has been aroused …

In the present study, we examined electron microscopically and immunohistochemically the
effects of perindopril, an angiotensin-converting enzyme inhibitor, on renal microangiopathy …

In our study we investigated the effects of angiotensin converting enzyme inhibitor and
Angiotensin T1 receptor blocker at low-doses which do not affect blood pressure and renal …

Abstract Background/Aims: We studied the effect of the combined treatment with an
angiotensin-converting enzyme (ACE) inhibitor (ramipril) and eplerenone compared with …

Diabetic nephropathy becomes the single most frequent cause of end-stage renal disease.
The present study aimed therefore to investigate possible protective effect of eprosartan, an …