An overview of recent studies on the analysis of pharmaceutical polymorphs
Pharmaceutical solids are well known to be able to exist in different solid-state forms and
there are a wide variety of solid-state analytical techniques available to characterize …
there are a wide variety of solid-state analytical techniques available to characterize …
[图书][B] Solid state characterization of pharmaceuticals
RA Storey, I Ymén - 2011 - books.google.com
The field of solid state characterization is central to the pharmaceutical industry, as drug
products are, in an overwhelming number of cases, produced as solid materials. Selection of …
products are, in an overwhelming number of cases, produced as solid materials. Selection of …
Analytical techniques for quantification of amorphous/crystalline phases in pharmaceutical solids
The existence of different solid-state forms such as polymorphs, solvates, hydrates, and
amorphous form in pharmaceutical drug substances and excipients, along with their …
amorphous form in pharmaceutical drug substances and excipients, along with their …
Pharmaceutical cocrystals, salts and polymorphs: Advanced characterization techniques
E Pindelska, A Sokal, W Kolodziejski - Advanced drug delivery reviews, 2017 - Elsevier
The main goal of a novel drug development is to obtain it with optimal physiochemical,
pharmaceutical and biological properties. Pharmaceutical companies and scientists modify …
pharmaceutical and biological properties. Pharmaceutical companies and scientists modify …
Analysis of solid-state transformations of pharmaceutical compounds using vibrational spectroscopy
Objectives Solid-state transformations may occur during any stage of pharmaceutical
processing and upon storage of a solid dosage form. Early detection and quantification of …
processing and upon storage of a solid dosage form. Early detection and quantification of …
Crystalline solids
SR Vippagunta, HG Brittain, DJW Grant - Advanced drug delivery reviews, 2001 - Elsevier
Many drugs exist in the crystalline solid state due to reasons of stability and ease of handling
during the various stages of drug development. Crystalline solids can exist in the form of …
during the various stages of drug development. Crystalline solids can exist in the form of …
Polymorphism and crystallization of active pharmaceutical ingredients (APIs)
Active pharmaceutical ingredients (APIs), frequently delivered to the patient in the solid-state
as part of an approved dosage form, can exist in such diverse solid forms as polymorphs …
as part of an approved dosage form, can exist in such diverse solid forms as polymorphs …
Solid forms of pharmaceuticals: Polymorphs, salts and cocrystals
B Sarma, J Chen, HY Hsi, AS Myerson - Korean Journal of Chemical …, 2011 - Springer
Control and selection of the properties of active pharmaceutical ingredients is a crucial part
of the drug development process. One major part of this process is the selection of an …
of the drug development process. One major part of this process is the selection of an …
The relevance of crystal forms in the pharmaceutical field: sword of damocles or innovation tools?
This review is aimed to provide to an “educated but non-expert” readership and an overview
of the scientific, commercial, and ethical importance of investigating the crystalline forms …
of the scientific, commercial, and ethical importance of investigating the crystalline forms …
Solid-state analysis of the active pharmaceutical ingredient in drug products
AW Newman, SR Byrn - Drug discovery today, 2003 - Elsevier
The solid form of a drug substance is important when developing a new chemical entity. The
crystalline form used in development is significant based on possible manufacturability …
crystalline form used in development is significant based on possible manufacturability …