Sickle cell disease (SCD) is a group of inherited disorders caused by a mutation of the
hemoglobin gene, resulting in the formation of abnormal, sickle-shaped red blood cells. It is …

Sickle cell disease (SCD) is an autosomal recessive disorder that results in hemolytic
anemia related to abnormal hemoglobin and erythrocyte levels. SCD is characterized by …

In sickle cell disease, various disturbances commonly affect the bones and joints. Vaso-
occlusive events in blood vessels that traverse the bones cause acute and chronic morbidity …

Sickle cell disease (SCD) is a genetic blood disorder caused by abnormal hemoglobin that
damages and deforms red blood cells (RBCs). The abnormal red cells break down, causing …

Sickle cell disease (SCD) is an autosomal recessive genetic condition that alters the shape
and function of the hemoglobin molecule in red blood cells. While the overall survival rate …

Drs Sathappan, Ginat, and Di Cesare are from the Musculoskeletal Research Center, NYU
Hospital for Joint Diseases, Department of Orthopedic Surgery, New York, NY. Drs …

Sickle cell anaemia is an autosomal recessive genetic condition producing abnormal
haemoglobin HbS molecules that result in stiff and sticky red blood cells leading to …

Sickle cell disease (SCD) is an inherited disorder of abnormal haemoglobin commonly
encountered in the West African sub-region. It has varied osteoarticular and non-osseous …

The sickle cell gene is pleiotropic in nature. Although it is a single gene mutation, it has
multiple phenotypic expressions that constitute the complications of sickle cell disease. The …

Abstract In the United States, sickle cell disease primarily affects people of Mrican descent,
and the multisystemic complications caused by the resultant vasoocclusive state create a …