The acute respiratory distress (ARDS) lung is usually characterized by a high degree of
inhomogeneity. Indeed, the same lung may show a wide spectrum of aeration alterations …

Background High inspiratory flow might damage the lungs by mechanisms not fully
understood yet. We hypothesized that increasing inspiratory flow would increase lung stress …

Background Lung-protective ventilation strategy suggests the use of low tidal volume,
depending on ideal body weight, and adequate levels of PEEP. However, reducing tidal …

Background Several studies have found only a weak to moderate correlation between
oxygenation and lung aeration in response to changes in PEEP. This study aimed to …

Purpose In the acute respiratory distress syndrome (ARDS), decreasing Ventilation-
Perfusion V˙/Q˙ mismatch might enhance lung protection. We investigated the regional …

Introduction Direct comparison of the relative efficacy of different recruitment maneuvers
(RMs) for patients with acute respiratory distress syndrome (ARDS) via clinical trials is …

Background Acute respiratory distress syndrome (ARDS) is a heterogeneous syndrome, and
the identification of homogeneous subgroups and phenotypes is the first step toward …

Background In ARDS patients, mechanical ventilation should minimize ventilator-induced
lung injury. The mechanical power which is the energy per unit time released to the …

Acute respiratory distress syndrome (ARDS) and acute lung injury are among the most
frequent reasons for intensive care unit admission, accounting for approximately one-third of …

Introduction To investigate the effects of positive end-expiratory pressure (PEEP) on
respiratory function and hemodynamics in patients with acute lung injury (ALI) or acute …