Acute myeloid leukemia in children: emerging paradigms in genetics and new approaches to therapy

SE Conneely, AM Stevens - Current oncology reports, 2021 - Springer
Abstract Purpose of Review Acute myeloid leukemia (AML) in children remains a
challenging disease to cure with suboptimal outcomes particularly when compared to the …

Acute myeloid leukemia in children: Current status and future directions

T Taga, D Tomizawa, H Takahashi… - Pediatrics …, 2016 - Wiley Online Library
Acute myeloid leukemia (AML) accounts for 25% of pediatric leukemia and affects
approximately 180 patients annually in Japan. The treatment outcome for pediatric AML has …

Childhood acute myeloid leukemia

JE Rubnitz - Current Treatment Options in Oncology, 2008 - Springer
Opinion statement Despite the use of intensive chemotherapy and hematopoietic stem cell
transplantation, approximately one-third of children with acute myeloid leukemia (AML) still …

Pediatric acute myeloid leukemia: updates on biology, risk stratification, and therapy

CW Elgarten, R Aplenc - Current Opinion in Pediatrics, 2020 - journals.lww.com
Further incorporation of genomic and molecular data in pediatric AML will allow for
additional refinements in risk stratification to enable the tailoring of treatment intensity. These …

Current management of childhood acute myeloid leukemia

JE Rubnitz - Pediatric Drugs, 2017 - Springer
The outcome for children with acute myeloid leukemia (AML) has improved significantly over
the past 30 years, with complete remission and overall survival rates exceeding 90 and …

Childhood acute myeloid leukaemia

JE Rubnitz, H Inaba - British journal of haematology, 2012 - Wiley Online Library
Although acute myeloid leukaemia (AML) has long been recognized for its morphological
and cytogenetic heterogeneity, recent high‐resolution genomic profiling has demonstrated a …

Overview of therapy and strategies for optimizing outcomes in de novo pediatric acute myeloid leukemia

K Faulk, L Gore, T Cooper - Pediatric Drugs, 2014 - Springer
Although acute myelogenous leukemia (AML) accounts for< 20% of leukemia in children, it
is responsible for over half of all pediatric leukemia deaths. Improvement in event-free …

Pediatric acute myeloid leukemia—past, present, and future

D Reinhardt, E Antoniou, K Waack - Journal of clinical medicine, 2022 - mdpi.com
JCM | Free Full-Text | Pediatric Acute Myeloid Leukemia&mdash;Past, Present, and Future Next
Article in Journal Sexual Habits and Sexual Dysfunctions in a Sample of Patients with Psychotic …

Acute myeloid leukaemia in children

PB Langmuir, R Aplenc, BJ Lange - Best Practice & Research Clinical …, 2001 - Elsevier
Acute myeloid leukaemia (AML) is characterized by a block in differentiation and an
unregulated proliferation of myeloid progenitor cells. While the cause of AML in children is …

[HTML][HTML] Pediatric acute myeloid leukemia: towards high-quality cure of all patients

GJL Kaspers, CM Zwaan - haematologica, 2007 - haematologica.org
Prognosis of childhood acute myeloid leukemia (AML) has improved significantly over the
past decades, from nearly no child surviving to a present probability of cure of approximately …