Biology, risk stratification, and therapy of pediatric acute leukemias: an update

CH Pui, WL Carroll, S Meshinchi… - Journal of clinical …, 2011 - ascopubs.org
Purpose We review recent advances in the biologic understanding and treatment of
childhood acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML), identify …

Acute myeloid leukemia in adolescents and young adults: challenging aspects

JM Rowe, Y Ofran - Acta haematologica, 2014 - karger.com
Treating adolescents and young adults (AYAs) diagnosed with cancer is a challenge. Acute
myeloid leukemia (AML) which is usually diagnosed in a previously healthy kid, requiring …

Pediatric acute myeloid leukemia: international progress and future directions

GJL Kaspers, U Creutzig - Leukemia, 2005 - nature.com
The prognosis of pediatric acute myeloid leukemia (AML) has improved significantly over the
past decades. However, few papers have actually illustrated this improvement, and many …

Diagnosis and management of acute myeloid leukemia in children and adolescents: recommendations from an international expert panel

U Creutzig, MM van Den Heuvel-Eibrink… - Blood, The Journal …, 2012 - ashpublications.org
Despite major improvements in outcome over the past decades, acute myeloid leukemia
(AML) remains a life-threatening malignancy in children, with current survival rates of∼ …

Cytogenetics of childhood acute myeloid leukemia: United Kingdom Medical Research Council Treatment trials AML 10 and 12

CJ Harrison, RK Hills, AV Moorman… - Journal of clinical …, 2010 - ascopubs.org
Purpose Karyotype is an independent indicator of prognosis in acute myeloid leukemia
(AML) that is widely applied to risk-adapted therapy. Because AML is rare in children, the …

Diagnosis and treatment of childhood acute myelogenous leukemia

DH Ebb, HJ Weinstein - Pediatric Clinics of North America, 1997 - Elsevier
Acute myelogenous leukemia (AML) accounts for about 20% of the acute leukemias seen in
children. In contrast to childhood acute lymphoblastic leukemia (ALL), only modest …

Recent advances in management of acute leukaemia

JM Chessells - Archives of disease in childhood, 2000 - adc.bmj.com
There have been significant improvements in the outlook for children with acute leukaemia
but these advances are only available to a minority of the world's children. There is still room …

Prognostic factors in pediatric acute myeloid leukemia

M Radhi, S Meshinchi, A Gamis - Current hematologic malignancy reports, 2010 - Springer
Acute myeloid leukemia (AML), a heterogeneous group of diseases with variable responses
to the same therapy, comprises nearly a quarter of childhood acute leukemias. Although …

Children's Oncology Group's 2023 blueprint for research: Myeloid neoplasms

TM Cooper, TA Alonzo, SK Tasian… - Pediatric Blood & …, 2023 - Wiley Online Library
During the past decade, the outcomes of pediatric patients with acute myeloid leukemia
(AML) have plateaued with 5‐year event‐free survival (EFS) and overall survival (OS) of …

Collaborative efforts driving progress in pediatric acute myeloid leukemia

CM Zwaan, EA Kolb, D Reinhardt… - Journal of clinical …, 2015 - ascopubs.org
Diagnosis, treatment, response monitoring, and outcome of pediatric acute myeloid
leukemia (AML) have made enormous progress during the past decades. Because AML is a …