Biology of childhood acute lymphoblastic leukemia

LL Nigro - Journal of pediatric hematology/oncology, 2013 - journals.lww.com
Acute lymphoblastic leukemia (ALL) is the most common malignancy in childhood,
accounting for almost 30% of pediatric cancers. Despite the high rate of cure, ALL is one of …

[HTML][HTML] Integrative analysis of type-I and type-II aberrations underscores the genetic heterogeneity of pediatric acute myeloid leukemia

BV Balgobind, IHIM Hollink, ST Arentsen-Peters… - …, 2011 - ncbi.nlm.nih.gov
Background Several studies of pediatric acute myeloid leukemia have described the various
type-I or type-II aberrations and their relationship with clinical outcome. However, there has …

Acute leukemia in infants

A Ibrahimova, L Pommert, EH Breese - Current Oncology Reports, 2021 - Springer
Abstract Purpose of the Review Infant leukemia is a rare, distinct subgroup of pediatric acute
leukemias diagnosed in children under 1 year of age and characterized by unique …

Acute lymphoblastic leukemia in children: an update of clinical, biological, and therapeutic aspects

DR Miller, LP Miller - Critical Reviews in Oncology/Hematology, 1990 - Elsevier
Acute Iymphoblastic leukemia (ALL), previously reviewed in this journal 5 years
ago,'remains the most common cancer and the second leading cause of death in children …

Treatment and biology of pediatric acute lymphoblastic leukemia

M Kato, A Manabe - Pediatrics International, 2018 - Wiley Online Library
Acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy. In the past
ALL was intractable but now the survival probability is as high as 80–90%. Improved …

Pediatric Oncology Group (POG) studies of acute myeloid leukemia (AML): a review of four consecutive childhood AML trials conducted between 1981 and 2000

Y Ravindranath, M Chang, CP Steuber, D Becton… - Leukemia, 2005 - nature.com
From 1981 to 2000, a total of 1823 children with acute myeloid leukemia (AML) enrolled on
four consecutive Pediatric Oncology Group (POG) clinical trials. POG 8101 demonstrated …

Possibilities for tailored and targeted therapy in paediatric acute myeloid leukaemia

CM Zwaan, GJL Kaspers - British journal of haematology, 2004 - Wiley Online Library
The clinical outcome of acute myeloid leukaemia (AML) in children has improved
considerably using intensive chemotherapy and/or stem cell transplantation. This leads to …

Acute myeloid leukaemia in childhood: clinical features and prognosis

JM Chessells, U Ocallaghan… - British journal of …, 1986 - Wiley Online Library
Clinical and laboratory features at presentation were correlated with morphological (FAB)
subclass of AML in a group of 112 children diagnosed between 1972 and 1982. Patients …

Acute myeloid leukemia: advancements in diagnosis and treatment

MG Yu, HY Zheng - Chinese medical journal, 2017 - mednexus.org
Objective: Leukemia is the most common pediatric malignancy and a major cause of
morbidity and mortality in children. Among all subtypes, a lack of consensus exists regarding …

Transcriptome analysis offers a comprehensive illustration of the genetic background of pediatric acute myeloid leukemia

N Shiba, K Yoshida, Y Hara, G Yamato… - Blood …, 2019 - ashpublications.org
Recent advances in the genetic understanding of acute myeloid leukemia (AML) have
improved clinical outcomes in pediatric patients. However,∼ 40% of patients with pediatric …