Impaired glucose tolerance after streptozotocin microinjection into the mediodorsal prefrontal cortex of the rat

B Nagy, I Szabo, G Takacs, B Csetényi… - Physiology …, 2016 - akjournals.com
The mediodorsal prefrontal cortex (mdPFC) is a key structure of the central glucose-
monitoring (GM) neural network. Previous studies indicate that intracerebral streptozotocin …

Effect of streptozotocin-induced diabetes on motor representations in the motor cortex and corticospinal tract in rats

K Muramatsu, M Ikutomo, T Tamaki, S Shimo, M Niwa - Brain research, 2018 - Elsevier
Motor disorders in patients with diabetes are associated with diabetic peripheral neuropathy,
which can lead to symptoms such as lower extremity weakness. However, it is unclear …

Investigating Cerebral Neurovascular Responses to Hyperglycemia in a Rat Model of Type 2 Diabetes Using Multimodal Assessment Techniques

S Yen, Y Wang, LD Liao - iScience, 2024 - cell.com
To study neurovascular function in type 2 diabetes mellitus (T2DM), we established a high-
fat diet/streptozotocin (HFD/STZ) rat mode. Electrocorticography–laser speckle contrast …

[HTML][HTML] Effects of exercise on brain functions in diabetic animal models

SS Yi - World Journal of Diabetes, 2015 - ncbi.nlm.nih.gov
Human life span has dramatically increased over several decades, and the quality of life has
been considered to be equally important. However, diabetes mellitus (DM) characterized by …

Rosiglitazone improves learning and memory ability in rats with type 2 diabetes through the insulin signaling pathway

L Ma, Z Shao, R Wang, Z Zhao, W Dong… - The American Journal of …, 2015 - Elsevier
Diabetes mellitus (DM) is associated with moderate cognitive deficits and neurophysiologic
and structural changes in the brain, a condition that is referred to as diabetic …

MODELO DE INDUÇÃO DO DIABETES MELLITUS E AVALIAÇÃO DA CARDIOMIOPATIA DIABÉTICA EM RATOS WISTAR MACHOS (Rattus novergicus)

L da Silva Mascarenhas, F Antunes, POB de Jesus - editoraessentia.iff.edu.br
O diabetes mellitus (DM) consiste em uma desordem metabólica complexa. O seu
aparecimento deve-se à deficiência de insulina devido à alteração pancreática, em que há …

Spatial memory impairments in a prediabetic rat model

E Soares, RD Prediger, S Nunes, AA Castro, SD Viana… - Neuroscience, 2013 - Elsevier
Diabetes is associated with an increased risk for brain disorders, namely cognitive
impairments associated with hippocampal dysfunction underlying diabetic encephalopathy …

Cognitive decline in STZ-3V rats is largely due to dysfunctional insulin signalling through the dentate gyrus

AS Shingo, T Kanabayashi, T Murase, S Kito - Behavioural brain research, 2012 - Elsevier
Recent epidemiological studies have associated type 2 diabetes mellitus with an increased
risk of developing Alzheimer's disease (AD). A dramatic decrease in glucose utilisation has …

Altered cerebral glucose metabolism in an animal model of diabetes insipidus: a micro-PET study

A Idbaih, A Burlet, H Adle-Biassette, R Boisgard… - Brain research, 2007 - Elsevier
The Brattleboro rat is an animal model of genetically induced central diabetes insipidus.
These rats show cognitive and behavioral disorders, but no neurodegenerative disease has …

Effects of experimental diabetes on cerebellar oxidative stress and motor function.

B Altuğ, İ Turan, B Onar… - … : International Journal of …, 2019 - search.ebscohost.com
Objective: Diabetes mellitus (DM) is a chronic disease with high mortality and morbidity
risks. It is well established that diabetes-related alteration of the central nervous system …