Affective and Cognitive Impairments in Rodent Models of Diabetes

E Palazzo, I Marabese, S Boccella… - Current …, 2024 - ingentaconnect.com
Diabetes and related acute and long-term complications have a profound impact on
cognitive, emotional, and social behavior, suggesting that the central nervous system (CNS) …

Time-dependent impairments in learning and memory in Streptozotocin-induced hyperglycemic rats

A Ahmed, G Zeng, D Jiang, H Lin, M Azhar… - Metabolic brain …, 2019 - Springer
The sedentary lifestyle is responsible for the high prevalence of diabetes which also impairs
cognition including learning and memory. Various studies have highlighted the learning and …

Region-specific metabolic characterization of the type 1 diabetic brain in mice with and without cognitive impairment

P Xu, J Ning, Q Jiang, C Li, J Yan, L Zhao… - Neurochemistry …, 2021 - Elsevier
Abstract Type 1 diabetes (T1D) has been reported to cause cognitive decline, but brain
metabolic changes during this process are still far from being fully understood. Here, we …

Efeito da estreptozotocina sobre os perfis glicêmico e lipídico eo estresse oxidativo em hamsters

M Silva, WG Lima, ME Silva… - Arquivos Brasileiros de …, 2011 - SciELO Brasil
OBJETIVO: Este estudo avaliou os efeitos da estreptozotocina nos perfis glicêmico e lipídico
e marcadores de estresse oxidativo em hamsteres. MATERIAIS E MÉTODOS: Hamsteres …

[HTML][HTML] Treadmill training improves motor skills and increases tyrosine hydroxylase immunoreactivity in the substantia nigra pars compacta in diabetic rats

PS do Nascimento, GA Lovatel, S Barbosa, J Ilha… - Brain research, 2011 - Elsevier
The aim of this study was to evaluate the effects of treadmill training on motor skills and
immunoreactivity to tyrosine hydroxylase in the substantia nigra pars compacta and ventral …

Sex differences in the effect of diabetes on cerebral glucose metabolism

CY Wu, YH Lin, HH Hsieh, JJ Lin, SL Peng - Biomedicines, 2021 - mdpi.com
The neuroimaging literature indicates that brain structure and function both deteriorate with
diabetes, but information on sexual dimorphism in diabetes-related brain alterations is …

Efeito do diabete na presença ou ausência da insulina na produção e atividade de enzimas chave do metabolismo energético em glândulas submandibulares de …

MS Pedrosa - 2022 - teses.usp.br
O objetivo deste estudo foi verificar o efeito do diabete (DM) na presença ou ausência da
insulina na expressão, quantidade e atividade de enzimas chaves do metabolismo …

Multimodal Comparison of Diabetic Neuropathy in Aged Streptozotocin-Treated Sprague–Dawley and Zucker Diabetic Fatty Rats

A Canta, VA Carozzi, A Chiorazzi, C Meregalli… - Biomedicines, 2022 - mdpi.com
The development and progression of diabetic polyneuropathy (DPN) are due to multiple
mechanisms. The creation of reliable animal models of DPN has been challenging and this …

Induction of diabetes in Wistar rats: is the streptozotocin model feasible at any age?

TC Mendes, GR da Silva… - Brazilian Journal …, 2020 - ojs.brazilianjournals.com.br
Diabetes mellitus (DM) is an epidemic that affects millions of people worldwide. Because of
its high morbidity and mortality, animal models of diabetes are indispensable to achieve a …

Neurofunctional evaluation of young male offspring of rat dams with diabetes induced by streptozotocin

C Delascio Lopes, R Sinigaglia-Coimbra… - International …, 2011 - Wiley Online Library
Diabetes mellitus (DM) is a complex disease, being one of the most prevalent diseases
worldwide. As a consequence, pregnancy‐associated diabetes is increasingly common …