The “French Paradox” and beyond: neuroprotective effects of polyphenols

AY Sun, A Simonyi, GY Sun - Free Radical Biology and Medicine, 2002 - Elsevier
Chronic ethanol ingestion is known to cause oxidative damage to a number of organs
including the brain. This is partly due to the ability of ethanol to enhance oxygen free radical …

Potential mechanism by which resveratrol, a red wine constituent, protects neurons

H Zhuang, YUNS KIM, RC Koehler… - Annals of the New York …, 2003 - Wiley Online Library
Polyphenolic compounds, such as resveratrol, are naturally present at high concentration in
grape skin, seeds, and red wine. Resveratrol is present in cis and trans isoforms and the …

Unique properties of polyphenol stilbenes in the brain: more than direct antioxidant actions; gene/protein regulatory activity

S Doré - Neurosignals, 2005 - karger.com
Abstract The 'French Paradox'has been typically associated with moderate consumption of
wine, especially red wine. A polyphenol 3, 4', 5-trihydroxy-trans-stilbene (a member of the …

Wine polyphenols: potential agents in neuroprotection

A Basli, S Soulet, N Chaher, JM Mérillon… - Oxidative medicine …, 2012 - Wiley Online Library
There are numerous studies indicating that a moderate consumption of red wine provides
certain health benefits, such as the protection against neurodegenerative diseases. This …

Antioxidant, anti-inflammatory and neuroprotective actions of resveratrol after experimental nervous system insults. Special focus on the molecular mechanisms …

CA Miguel, MV Noya-Riobó, GL Mazzone… - Neurochemistry …, 2021 - Elsevier
After different types of acute central nervous system insults, including stroke, subarachnoid
haemorrhage and traumatic brain and spinal cord injuries, secondary damage plays a …

[HTML][HTML] Neuroprotective action of resveratrol

S Bastianetto, C Ménard, R Quirion - Biochimica et Biophysica Acta (BBA) …, 2015 - Elsevier
Low-to-moderate red wine consumption appeared to reduce age-related neurological
disorders including macular degeneration, stroke, and cognitive deficits with or without …

Neuroprotective effects of resveratrol and epigallocatechin gallate polyphenols are mediated by the activation of protein kinase C gamma

C Menard, S Bastianetto, R Quirion - Frontiers in cellular …, 2013 - frontiersin.org
Polyphenols such as epigallocatechin gallate (EGCG) and resveratrol have received a great
deal of attention because they may contribute to the purported neuroprotective action of the …

Ethanol and oxidative mechanisms in the brain

AY Sun, GY Sun - Journal of Biomedical Science, 2001 - karger.com
There is strong evidence showing that chronic and excessive ethanol consumption may
enhance oxidative damage to neurons and result in cell death. Although not yet well …

Wine and oxidative stress: up-to-date evidence of the effects of moderate wine consumption on oxidative damage in humans

MI Covas, P Gambert, M Fitó, R de la Torre - Atherosclerosis, 2010 - Elsevier
Wine and alcohol consumption has been considered to be protective against coronary heart
disease development, an oxidative stress associated disease. Wine contains polyphenols …

Partial neuroprotection of in vivo excitotoxic brain damage by chronic administration of the red wine antioxidant agent, trans-resveratrol in rats

M Virgili, A Contestabile - Neuroscience letters, 2000 - Elsevier
The antioxidant compound trans-resveratrol, is found in substantial amount in several types
of red wine and is considered one of the substances responsible for the lower incidence of …