[HTML][HTML] Human papillomavirus genomics: Understanding carcinogenicity
CW Nelson, L Mirabello - Tumour Virus Research, 2023 - Elsevier
Human papillomavirus (HPV) causes virtually all cervical cancers and many cancers at other
anatomical sites in both men and women. However, only 12 of 448 known HPV types are …
anatomical sites in both men and women. However, only 12 of 448 known HPV types are …
[HTML][HTML] The intersection of HPV epidemiology, genomics and mechanistic studies of HPV-mediated carcinogenesis
Of the~ 60 human papillomavirus (HPV) genotypes that infect the cervicovaginal epithelium,
only 12–13 “high-risk” types are well-established as causing cervical cancer, with HPV16 …
only 12–13 “high-risk” types are well-established as causing cervical cancer, with HPV16 …
Human papillomavirus genomics: past, present and future
Human papillomaviruses (HPV) are a group of divergent DNA viruses, of which a select few
evolutionarily related HPVs have emerged to be highly oncogenic and of significant medical …
evolutionarily related HPVs have emerged to be highly oncogenic and of significant medical …
Human papillomaviruses: genetic basis of carcinogenicity
Persistent infection by specific oncogenic human papillomaviruses (HPVs) is established as
the necessary cause of cervix cancer. DNA sequence differences between HPV genomes …
the necessary cause of cervix cancer. DNA sequence differences between HPV genomes …
A population-based prospective study of carcinogenic human papillomavirus variant lineages, viral persistence, and cervical neoplasia
M Schiffman, AC Rodriguez, Z Chen, S Wacholder… - Cancer research, 2010 - AACR
Human papillomavirus (HPV) types differ profoundly in cervical carcinogenicity. For the most
carcinogenic type HPV16, variant lineages representing further evolutionary divergence …
carcinogenic type HPV16, variant lineages representing further evolutionary divergence …
Within-host variations of human papillomavirus reveal APOBEC signature mutagenesis in the viral genome
Y Hirose, M Onuki, Y Tenjimbayashi, S Mori… - Journal of …, 2018 - Am Soc Microbiol
Persistent infection with oncogenic human papillomaviruses (HPVs) causes cervical cancer,
accompanied by the accumulation of somatic mutations into the host genome. There are …
accompanied by the accumulation of somatic mutations into the host genome. There are …
[HTML][HTML] Classification and evolution of human papillomavirus genome variants: Alpha-5 (HPV26, 51, 69, 82), Alpha-6 (HPV30, 53, 56, 66), Alpha-11 (HPV34, 73) …
HPV variants from the same type can be classified into lineages and sublineages based on
the complete genome differences and the phylogenetic topologies. We examined nucleotide …
the complete genome differences and the phylogenetic topologies. We examined nucleotide …
[HTML][HTML] HPV16 E7 genetic conservation is critical to carcinogenesis
Although most cervical human papillomavirus type 16 (HPV16) infections become
undetectable within 1–2 years, persistent HPV16 causes half of all cervical cancers. We …
undetectable within 1–2 years, persistent HPV16 causes half of all cervical cancers. We …
Genetic variations in human papillomavirus and cervical cancer outcomes
JS Rader, SW Tsaih, D Fullin… - … journal of cancer, 2019 - Wiley Online Library
Cervical cancer is driven by persistent infection of human papillomavirus (HPV), which is
influenced by HPV type and intratypic variants, yet the impact of HPV type and intratypic …
influenced by HPV type and intratypic variants, yet the impact of HPV type and intratypic …
[HTML][HTML] Intra-host sequence variability in human papillomavirus
RSD Mandishora, KS Gjøtterud, S Lagström… - Papillomavirus …, 2018 - Elsevier
Human papillomaviruses (HPVs) co-evolve slowly with the human host and each HPV
genotype displays epithelial tropisms. We assessed the evolution of intra HPV genotype …
genotype displays epithelial tropisms. We assessed the evolution of intra HPV genotype …