Background Sarcopenia was recently recognized as an independent condition by an
International Classification of Diseases, Tenth Revision, Clinical Modification code, and is a …

The awareness of the presence and consequences of sarcopenia has significantly
increased over the past decade. Sarcopenia is defined as gradual loss of muscle mass and …

Chronic obstructive pulmonary disease (COPD) is a common pulmonary disease
characterized by persistent respiratory symptoms and airflow obstruction. In addition to lung …

Background Quadriceps muscle fiber atrophy and a loss of oxidative type I muscle fibers and
mitochondrial content often occur in chronic obstructive pulmonary disease (COPD), which …

Rationale Muscle atrophy confers a poor prognosis in patients with chronic obstructive
pulmonary disease (COPD), yet the molecular pathways responsible are poorly …

Skeletal muscle atrophy in individuals with advanced chronic obstructive pulmonary disease
(COPD) is associated with diminished quality of life, increased health resource use, and …

Patients with chronic obstructive pulmonary disease (COPD) experience several systemic
manifestations such skeletal muscle dysfunction with and without muscle mass loss …

Patients with stable chronic obstructive pulmonary disease (COPD) frequently exhibit
unintentional accentuated peripheral muscle loss and dysfunction. Skeletal muscle mass in …

Rationale: The molecular mechanisms of muscle atrophy in chronic obstructive pulmonary
disease (COPD) are poorly understood. In wasted animals, muscle mass is regulated by …

Background Age-related loss of muscle, sarcopenia, is recognised as a clinical syndrome
with multiple contributing factors. International European Working Group on Sarcopenia in …