While previous studies have identified cancer stem‐like cells (CSCs) as a crucial driver for
chemoresistance and tumor recurrence, the underlying mechanisms for populating the CSC …

Cancer stem cells (CSCs) are distinct subpopulations of cancer cells with stem cell-like
abilities and are more resilient to chemotherapy, causing tumor relapse. Mitophagy, a …

Cancer stem–like cells (CSC) are thought to drive tumor initiation, metastasis, relapse, and
therapeutic resistance, but their specific pathogenic characters in many cancers, including …

Oncogenic signaling pathway reprograms cancer cell metabolism to promote aerobic
glycolysis in favor of tumor growth. The ability of cancer cells to evade immunosurveillance …

Cancer stem-like cells (CSCs) are critically involved in cancer metastasis and
chemoresistance, acting as one major obstacle in clinical practice. While accumulating …

T cell exhaustion is an obstacle to immunotherapy for solid tumors. An understanding of the
mechanism by which T cells develop this phenotype in solid tumors is needed. Here …

The selective autophagic degradation of mitochondria via mitophagy is essential for
preserving mitochondrial homeostasis and, thereby, disease maintenance and progression …

Mitophagy regulates cancer stem cell (CSC) populations affecting tumorigenicity and
malignancy in various cancer types. Here, we report that cisplatin treatment led to the …

The host immune system plays a pivotal role in the emergence of tumor cells that are
refractory to multiple clinical interventions including immunotherapy, chemotherapy, and …

Mitochondria (MT) participate in most metabolic activities of mammalian cells. A near-
unidirectional mitochondrial transfer from T cells to cancer cells was recently observed to" …