The fate of nanocarriers as nanomedicines in vivo: important considerations and biological barriers to overcome

M Moros, SG Mitchell, V Grazu - Current Medicinal Chemistry, 2013 - ingentaconnect.com
Many pharmaceuticals on the market suffer from two significant limitations to their activity:
lack of specificity toward the pathological site and poor aqueous solubility. Both factors …

Effect of physicochemical and surface properties on in vivo fate of drug nanocarriers

Z Zhao, A Ukidve, V Krishnan, S Mitragotri - Advanced drug delivery …, 2019 - Elsevier
Over the years, a plethora of materials–natural and synthetic–have been engineered at a
nanoscopic level and explored for drug delivery. Nanocarriers based on such materials …

Nanocarriers in different preclinical and clinical stages

SN Abed, PK Deb, HS Surchi, SF Kokaz… - Basic fundamentals of …, 2019 - Elsevier
Nanotechnology is a newly emerging branch of science for designing particles of sizes
ranging from 1 to 1000 nm. These nanobased systems elicit specific function at the cellular …

[PDF][PDF] Unraveling the in vivo fate and cellular pharmacokinetics of drug nanocarriers

W Wu, T Li - Adv Drug Deliv Rev, 2019 - researchgate.net
Research in nanocarrier-based drug delivery systems has exploded over recent years,
evidenced by an exponential increase in the number of publications. A casual search of …

Potential and applications of nanocarriers for efficient delivery of biopharmaceuticals

A Zeb, I Rana, HI Choi, CH Lee, SW Baek, CW Lim… - Pharmaceutics, 2020 - mdpi.com
During the past two decades, the clinical use of biopharmaceutical products has markedly
increased because of their obvious advantages over conventional small-molecule drug …

[PDF][PDF] Taking the vehicle out of drug delivery

J Shen, J Wolfram, M Ferrari, H Shen - Materials today, 2017 - Elsevier
The biodistribution of drugs has a major impact on therapeutic efficacy and side effects.
Previously, nanocarriers have been utilized to improve localized drug delivery, and there are …

[HTML][HTML] Recent advances in nanocarrier-assisted therapeutics delivery systems

S Su, PM Kang - Pharmaceutics, 2020 - mdpi.com
Nanotechnologies have attracted increasing attention in their application in medicine,
especially in the development of new drug delivery systems. With the help of nano-sized …

Nanocarriers for drug delivery: mini review

V Girdhar, S Patil, S Banerjee… - … : Recent Patents on …, 2018 - ingentaconnect.com
Background: Nanocarriers have been a part of drug delivery for some decades now. Due to
the enormous advantages offered by them, they are replacing the conventionally available …

Efficient Nanocarriers for drug-delivery systems: types and fabrication

RK Mishra, SK Tiwari, S Mohapatra… - Nanocarriers for drug …, 2019 - Elsevier
Drug delivery relates to techniques, originations, technology, and solutions for delivering
drug compounds inside the body as required to safely and securely fulfill their preferred …

Nano/microcarriers in drug delivery: moving the timeline to contemporary

AV Nikezić, JG Novaković - Current Medicinal Chemistry, 2023 - ingentaconnect.com
Treatment of various diseases, especially cancer treatment, includes the potential use of
different types of nanoparticles and nanostructures as drug carriers. However, searching for …