Magnetic resonance images of the lungs of a guinea pig have been produced using
hyperpolarized helium as the source of the MR signal. The resulting images are not yet …

The authors imaged the lungs of live guinea pigs with hyperpolarized (HP) helium-3 as a
magnetic resonance (MR) signal source. HP He-3 gas produced through spin exchange …

The nuclear spin polarization of noble gases can be enhanced strongly by laser optical
pumping followed by electron‐nuclear polarization transfer. Direct optical pumping of …

Optical polarization of 3He generates large nuclear spin magnetizations, allowing MR
imaging of the gas spaces of human and animal lungs despite the low number density of …

Rapid repetitive MRI of hyperpolarized (HP) gases using echo‐planar imaging (EPI) has
been theoretically investigated and experimentally demonstrated for 3He in human lung. A …

The nuclear spin polarization of the noble gas isotopes 3He and 129Xe can be increased
using optical pumping methods by four to five orders of magnitude. This extraordinary gain …

Magnetic resonance imaging using the MR signal from hyperpolarized noble gases 129Xe
and 3He may become an important new diagnostic technique. Alex Pines (adapting the …

Lung imaging has traditionally relied on x‐ray methods, since proton MRI is limited to some
extent by low proton density in the lung parenchyma and static field inhomogeneities in the …

By permitting direct visualization of the airspaces of the lung, magnetic resonance imaging
(MRI) using hyperpolarized gases provides unique strategies for evaluating pulmonary …

Two healthy volunteers who had inhaled approximately 0.75 L of laser-polarized helium-3
gas underwent magnetic resonance imaging at 1.5 T with fast gradient-echo pulse …