Conjugative relaxases are the proteins that initiate bacterial conjugation by a site-specific
cleavage of the transferred DNA strand. In vitro, they show strand-transferase activity on …

The conjugative transposon Tn916 encodes a protein called INT (Tn916) which, based on
DNA sequence comparisons, is a member of the integrase family of site-specific …

Site-specific recombinases (integrases) can mediate the horizontal transfer of genomic
islands. The ability to integrate large DNA sequences into target sites is very important for …

Although the integrase (IntDOT) of the Bacteroides conjugative transposon CTnDOT has
been classified as a member of the tyrosine recombinase family, the reaction it catalyzes …

The conjugative transposon Tn916 inserts with widely different frequencies into a variety of
target sites with related nucleotide sequences. The binding of chimeric proteins, consisting …

Integrative and conjugative elements (ICEs) are mobile genetic elements that can transfer by
conjugation to recipient cells. Some ICEs integrate into a unique site in the genome of their …

Transposition of the conjugative transposon Tn916 requires the activity of a protein, called
Int, which is related to members of the integrase family of site‐specific recombinases. This …

The Mycobacterium tuberculosis prophage‐like element φRv1 encodes a site‐specific
recombination system utilizing an integrase of the serine recombinase family …

Transposons are found in a wide variety of forms throughout the prokaryotic world where
they actively contribute to the adaptive strategies of bacterial communities and hence, to the …

TrwC is an essential protein in conjugative DNA transfer of the broad‐host‐range plasmid
R388. TrwC was purified in two chromatographic steps from TrwC‐overproducing bacteria …