Background A large subfamily of serine recombinases contains long polypeptide segments
appended to the C-terminal end of the conserved catalytic domain. Members of this …

DNA sequence database search revealed that most of Tn5053/Tn402 family transposons
inserted into natural plasmids were located in putative res regions upstream of genes …

Bacteria contain a large number of transposable elements that can be categorized in four
major groups according to their mechanisms of transposition. These are: class I: insertion …

On the strengths of forward genetics and embryology, the zebrafish Danio rerio has become
an ideal system for the study of early vertebrate development. However, additional tools will …

The site-specific integrase of actinophage R4 belongs to the serine recombinase family.
During the lysogenization process, it catalyzes site-specific recombination between the …

TrwC is required for conjugal DNA transfer of the broad host range plasmid R388. The
purified protein showsin vitroDNA helicase activity. Here we report that it also hasin vitro oriT …

ΦC31 integrase, a site-specific large serine recombinase, is a useful tool for genome
engineering in a variety of eukaryotic species and cell types. ΦC31 integrase performs …

Streptomyces phage integrase phiC31 is capable of mediating site-specific insertions in
mammalian genomes. To avoid potential toxicity of long-term expression of phiC31 in host …

Abstract Bacteriophage ${\Phi} FC1 $ integrase (MJ1) was previously shown to perform a
site-specific recombination between a phage attachment site (attP) and a host attachment …

In bacteria, two categories of specialised recombination promote a variety of DNA
rearrangements. Transposition is the process by which genetic elements move between …