Acute kidney injury (AKI) is a serious renal dysfunction syndromes, which predominantly
correlates with the excess production of endogenous reactive oxygen/nitrogen species …

Background Iron sulfide nanomaterials have been successfully employed as therapeutic
agents for bacterial infection therapy and catalytic-ferroptosis synergistic tumor therapy due …

Acute kidney injury (AKI) is a severe renal dysfunction syndrome associated with high
morbidity and mortality. Excessive production of reactive oxygen/nitrogen species (RONS) is …

Cellular redox homeostasis is highly dependent on endogenous antioxidant systems,
including superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) …

Ferroptosis is one critical kind of regulated cell death for tumor suppression, yet it still
presents challenges of low efficiency due to the intracellular alkaline pH and aberrant redox …

Ferroptosis is a novel type of nonapoptotic programmed cell death involving the
accumulation of lipid peroxidation (LPO) to a lethal threshold. Herein, we propose tunable …

Oxidative stress is a compelling risk factor in chronic kidney diseases and is further
aggravated for individuals during extracorporeal blood purification, ultimately leading to …

Background The reactive oxygen species (ROS) and inflammation, a critical contributor to
tissue damage, is well-known to be associated with various disease. The kidney is …

Emerging cancer cell ferroptosis features the direct depletion of glutathione (GSH) and
resultant chemical inhibition on glutathione peroxidase 4 (GPX4) bioactivity, which …

Ferroptosis is a programmed, iron-dependent, oxidative cell death that was discovered
recently. It is usually accompanied by iron accumulation and lipid peroxidation during the …