Cortical reactivity and effective connectivity during REM sleep in humans

M Massimini, F Ferrarelli, MJ Murphy… - Cognitive …, 2010 - Taylor & Francis
We recorded the electroencephalographic (EEG) responses evoked by transcranial
magnetic stimulation (TMS) during the first rapid eye movement (REM) sleep episode of the …

[HTML][HTML] Consciousness and cortical responsiveness: a within-state study during non-rapid eye movement sleep

JO Nieminen, O Gosseries, M Massimini, E Saad… - Scientific Reports, 2016 - nature.com
When subjects become unconscious, there is a characteristic change in the way the cerebral
cortex responds to perturbations, as can be assessed using transcranial magnetic …

Functional microstates within human REM sleep: first evidence from fMRI of a thalamocortical network specific for phasic REM periods

R Wehrle, C Kaufmann, TC Wetter… - European Journal of …, 2007 - Wiley Online Library
High thalamocortical neuronal activity characterizes both, wakefulness and rapid eye
movement (REM) sleep, but apparently this network fulfills other roles than processing …

Breakdown in cortical effective connectivity during midazolam-induced loss of consciousness

F Ferrarelli, M Massimini, S Sarasso… - Proceedings of the …, 2010 - National Acad Sciences
By employing transcranial magnetic stimulation (TMS) in combination with high-density
electroencephalography (EEG), we recently reported that cortical effective connectivity is …

[HTML][HTML] Connectivity differences between consciousness and unconsciousness in non-rapid eye movement sleep: a TMS–EEG study

M Lee, B Baird, O Gosseries, JO Nieminen, M Boly… - Scientific reports, 2019 - nature.com
The neuronal connectivity patterns that differentiate consciousness from unconsciousness
remain unclear. Previous studies have demonstrated that effective connectivity, as assessed …

Cortical mechanisms of loss of consciousness: insight from TMS/EEG studies

M Massimini, F Ferrarelli, S Sarasso… - Archives italiennes de …, 2012 - architalbiol.org
In a recent series of experiments we recorded the electroencephalogram (EEG) response to
a direct cortical stimulation in humans during wakefulness, NREM sleep, REM sleep and …

Hierarchical clustering of brain activity during human nonrapid eye movement sleep

M Boly, V Perlbarg, G Marrelec… - Proceedings of the …, 2012 - National Acad Sciences
Consciousness is reduced during nonrapid eye movement (NREM) sleep due to changes in
brain function that are still poorly understood. Here, we tested the hypothesis that impaired …

Brain activation and hypothalamic functional connectivity during human non-rapid eye movement sleep: an EEG/fMRI study

C Kaufmann, R Wehrle, TC Wetter, F Holsboer… - Brain, 2006 - academic.oup.com
Regional differences in sleep EEG dynamics indicate that sleep-related brain activity
involves local brain processes with sleep stage specific activity patterns of neuronal …

Human cortical excitability increases with time awake

R Huber, H Mäki, M Rosanova, S Casarotto… - Cerebral …, 2013 - academic.oup.com
Prolonged wakefulness is associated not only with obvious changes in the way we feel and
perform but also with well-known clinical effects, such as increased susceptibility to seizures …

Quantifying cortical EEG responses to TMS in (un) consciousness

S Sarasso, M Rosanova, AG Casali… - Clinical EEG and …, 2014 - journals.sagepub.com
We normally assess another individual's level of consciousness based on her or his ability to
interact with the surrounding environment and communicate. Usually, if we observe …