Conserved function of pex11p and the novel pex25p and pex27p in peroxisome biogenesis

H Rottensteiner, K Stein, E Sonnenhol… - Molecular Biology of …, 2003 - Am Soc Cell Biol
We describe the isolation and characterization of a homologous pair of proteins, Pex25p
(YPL112c) and Pex27p (YOR193w), whose C-termini are similar to the entire Pex11p. All …

Yarrowia lipolytica Cells Mutant for the Peroxisomal Peroxin Pex19p Contain Structures Resembling Wild-Type Peroxisomes

GR Lambkin, RA Rachubinski - Molecular Biology of the Cell, 2001 - Am Soc Cell Biol
PEX genes encode peroxins, which are proteins required for peroxisome assembly. The
PEX19 gene of the yeast Yarrowia lipolytica was isolated by functional complementation of …

[HTML][HTML] Cloning and characterization of the gene encoding the human peroxisomal assembly protein Pex3p

S Kammerer, A Holzinger, U Welsch, AA Roscher - FEBS letters, 1998 - Elsevier
Proteins essential for the assembly of functional peroxisomes are designated peroxins and
are encoded by PEX genes. In yeast, Pex3p was previously identified as a peroxisomal …

[HTML][HTML] Pex19p binds Pex30p and Pex32p at regions required for their peroxisomal localization but separate from their peroxisomal targeting signals

FJ Vizeacoumar, WN Vreden, JD Aitchison… - Journal of Biological …, 2006 - ASBMB
The assembly of proteins in the peroxisomal membrane is a multistep process requiring their
recognition in the cytosol, targeting to and insertion into the peroxisomal membrane, and …

The interaction between human PEX3 and PEX19 characterized by fluorescence resonance energy transfer (FRET) analysis

AC Muntau, AA Roscher, WH Kunau, G Dodt - European journal of cell …, 2003 - Elsevier
The process of peroxisome biogenesis involves several PEX genes that encode the
machinery required to assemble the organelle. Among the corresponding peroxins the …

The origin and maintenance of mammalian peroxisomes involves a de novo PEX16-dependent pathway from the ER

PK Kim, RT Mullen, U Schumann… - The Journal of cell …, 2006 - rupress.org
Peroxisomes are ubiquitous organelles that proliferate under different physiological
conditions and can form de novo in cells that lack them. The endoplasmic reticulum (ER) has …

Intra-ER sorting of the peroxisomal membrane protein Pex3 relies on its luminal domain

MH Fakieh, PJM Drake, J Lacey, JM Munck… - Biology …, 2013 - journals.biologists.com
Pex3 is an evolutionarily conserved type III peroxisomal membrane protein required for
peroxisome formation. It is inserted into the ER membrane and sorted via an ER subdomain …

PEX11 promotes peroxisome division independently of peroxisome metabolism

X Li, SJ Gould - The Journal of cell biology, 2002 - rupress.org
The PEX11 peroxisomal membrane proteins are the only factors known to promote
peroxisome division in multiple species. It has been proposed that PEX11 proteins have a …

PEX11α is required for peroxisome proliferation in response to 4-phenylbutyrate but is dispensable for peroxisome proliferator-activated receptor alpha-mediated …

X Li, E Baumgart, GX Dong, JC Morrell… - … and cellular biology, 2002 - Taylor & Francis
The PEX11 peroxisomal membrane proteins promote peroxisome division in multiple
eukaryotes. As part of our effort to understand the molecular and physiological functions of …

Yarrowia lipolytica Cells Mutant for thePEX24 Gene Encoding a Peroxisomal Membrane Peroxin Mislocalize Peroxisomal Proteins and Accumulate Membrane …

YYC Tam, RA Rachubinski - Molecular biology of the cell, 2002 - Am Soc Cell Biol
Peroxins are proteins required for peroxisome assembly and are encoded by the PEX
genes. Functional complementation of the oleic acid–nonutilizing strain mut1-1 of the yeast …