The biogenesis of peroxisomal matrix and membrane proteins is substantially different from
the biogenesis of proteins of other subcellular compartments, such as mitochondria and …

The biogenesis of peroxisomes requires the interaction of several peroxins, encoded by
PEX genes and is well conserved between yeast and humans. We have cloned the human …

PEX genes encode proteins (peroxins) that are required for the biogenesis of peroxisomes.
One of these peroxins, Pex5p, is the receptor for matrix proteins with a type 1 peroxisomal …

The Saccharomyces cerevisiae pex17-1 mutant was isolated from a screen to identify
mutants defective in peroxisome biogenesis. pex17-1 and pex17 null mutants fail to import …

Peroxisomes are subcellular organelles that play a central role in human physiology by
catalyzing a range of unique metabolic functions. The importance of peroxisomes for human …

Peroxisomes are a class of structurally and functionally related organelles present in almost
all eukaryotic cells. The importance of peroxisomes for human life is highlighted by severe …

Peroxisomes, as well as the signals and the machinery that target proteins to this organelle,
are conserved in most eukaryotic organisms. Different peroxisomal targeting signals (PTSs) …

Peroxisomes function together with mitochondria in a number of essential biochemical
pathways, from bile acid synthesis to fatty acid oxidation. Peroxisomes grow and divide from …

PEX5 encodes the type-1 peroxisomal targeting signal (PTS1) receptor, one of at least 15
peroxins required for peroxisome biogenesis. Pex5p has a bimodal distribution within the …

We demonstrate that the peroxin Pex3 is not required for the formation of peroxisomal
membrane structures in yeast pex3 mutant cells. Notably, pex3 mutant cells already contain …