Juliflorine: a potent natural peripheral anionic-site-binding inhibitor of acetylcholinesterase with calcium-channel blocking potential, a leading candidate for …
The alkaloid juliflorine (1) from Prosopis juliflora inhibited acetylcholinesterase (AChE, EC
3.1. 1.7) and butyrylcholinesterase (BChE, EC 3.1. 1.8) enzymes in a concentration …
3.1. 1.7) and butyrylcholinesterase (BChE, EC 3.1. 1.8) enzymes in a concentration …
Cholinesterase inhibitors assessment of aporphine alkaloids from Annona crassiflora and molecular docking studies
MF Barbosa, AB Justino, MM Martins, KRA Belaz… - Bioorganic …, 2022 - Elsevier
Annona crassiflora Mart. is an endemic plant from Brazilian Cerrado (savanna) biome,
commonly employed in traditional medicine to treat wounds, diarrhea, and scalp infections …
commonly employed in traditional medicine to treat wounds, diarrhea, and scalp infections …
Synthesis and cholinesterase inhibition of cativic acid derivatives
NP Alza, V Richmond, CJ Baier, E Freire… - Bioorganic & medicinal …, 2014 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder associated with memory
impairment and cognitive deficit. Most of the drugs currently available for the treatment of AD …
impairment and cognitive deficit. Most of the drugs currently available for the treatment of AD …
Neurologically Potent Molecules from Crataegus oxyacantha; Isolation, Anticholinesterase Inhibition, and Molecular Docking
Crataegus oxyacantha is an important herbal supplement and famous for its antioxidant
potential. The antioxidant in combination with anticholinesterase activity can be considered …
potential. The antioxidant in combination with anticholinesterase activity can be considered …
Isolation, identification, and quantification of Pentylcurcumene from Geophila repens: A new class of cholinesterase inhibitor for Alzheimer's disease
The aerial part of Geophila repens (L.) IM Johnst (Rubiaceae) has been used in India to
improve intelligence and memory for a long time. As part of our ongoing efforts in …
improve intelligence and memory for a long time. As part of our ongoing efforts in …
In Vitro and in Silico Analysis of Phytochemicals From Fallopia dentatoalata as Dual Functional Cholinesterase Inhibitors for the Treatment of Alzheimer's Disease
Y Wu, X Su, J Lu, M Wu, SY Yang, Y Mai… - Frontiers in …, 2022 - frontiersin.org
Current studies have found that butyrylcholinesterase (BuChE) replaces the biological
function of acetylcholinesterase (AChE) in the late stage of Alzheimer's disease. Species in …
function of acetylcholinesterase (AChE) in the late stage of Alzheimer's disease. Species in …
In vitro and in silico acetylcholinesterase inhibitory activity of thalictricavine and canadine and their predicted penetration across the blood-brain barrier
J Chlebek, J Korábečný, R Doležal, Š Štěpánková… - Molecules, 2019 - mdpi.com
In recent studies, several alkaloids acting as cholinesterase inhibitors were isolated from
Corydalis cava (Papaveraceae). Inhibitory activities of (+)-thalictricavine (1) and (+) …
Corydalis cava (Papaveraceae). Inhibitory activities of (+)-thalictricavine (1) and (+) …
Cholinesterase Inhibition Activity, Alkaloid Profiling and Molecular Docking of Chilean Rhodophiala (Amaryllidaceae)
Amaryllidaceae plants are the commercial source of galanthamine, an alkaloid approved for
the clinical treatment of Alzheimer's disease. The chemistry and bioactivity of Chilean …
the clinical treatment of Alzheimer's disease. The chemistry and bioactivity of Chilean …
Steroidal alkaloids from Holarrhena antidysenterica as acetylcholinesterase inhibitors and the investigation for structure–activity relationships
ZD Yang, DZ Duan, WW Xue, XJ Yao, S Li - Life sciences, 2012 - Elsevier
AIMS: Inhibition of acetylcholinesterase (AChE) is still considered as a strategy for the
treatment of neurological disorders such as Alzheimer's disease (AD). Many plant derived …
treatment of neurological disorders such as Alzheimer's disease (AD). Many plant derived …
Interaction study of two diterpenes, cryptotanshinone and dihydrotanshinone, to human acetylcholinesterase and butyrylcholinesterase by molecular docking and …
KKK Wong, JCK Ngo, S Liu, H Lin, C Hu… - Chemico-biological …, 2010 - Elsevier
Alzhemier's disease (AD) is a common form of dementia in the ageing population which is
characterized by depositions of amyloids and a cholinergic neurotransmission deficit in the …
characterized by depositions of amyloids and a cholinergic neurotransmission deficit in the …
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