Derivation and validation of four patient clusters in Still's disease, results from GIRRCS AOSD-study group and AIDA Network Still Disease Registry

P Ruscitti, F Masedu, A Vitale, I Di Cola, V Caggiano… - RMD open, 2023 - rmdopen.bmj.com
Background Different patient clusters were preliminarily suggested to dissect the clinical
heterogeneity in Still's disease. Thus, we aimed at deriving and validating disease clusters …

[HTML][HTML] Adult-Onset Still's Disease—A Complex Disease, a Challenging Treatment

LA Macovei, A Burlui, I Bratoiu, C Rezus… - International Journal of …, 2022 - mdpi.com
Adult-onset Still's disease (AOSD) is a systemic inflammatory disorder with an unknown
cause characterized by high-spiking fever, lymphadenopathy, hepatosplenomegaly …

[HTML][HTML] Adult-onset Still's disease: novel biomarkers of specific subsets, disease activity, and relapsing forms

B Maranini, G Ciancio, M Govoni - International Journal of Molecular …, 2021 - mdpi.com
Adult-onset Still's disease (AOSD) is a systemic inflammatory disease of unknown etiology.
Recent studies have demonstrated that the hallmark of AOSD is a cytokine storm, which is …

Management of adult-onset Still's disease: evidence-and consensus-based recommendations by experts

HL Leavis, PLA van Daele, C Mulders-Manders… - …, 2024 - academic.oup.com
Abstract Objectives Adult-onset Still's disease (AOSD) is a rare condition characterized by
fevers, rash, and arthralgia/arthritis; most doctors treating AOSD in the Netherlands treat< 5 …

Clinical characteristics and comorbidities in adult-onset Still's disease using a large US administrative claims database

A Lenert, GY Oh, MJ Ombrello, S Kim - Rheumatology, 2020 - academic.oup.com
Objectives We aimed to describe clinical characteristics, treatment patterns and major
comorbidities of a US-based adult-onset Still's disease (AOSD) cohort. Methods …

Systematic Review and Metaanalysis of Pharmacological Interventions in Adult-Onset Still Disease and the Role of Biologic Disease-Modifying Antirheumatic Drugs

P Ruscitti, D McGonagle, VC Garcia, H Rabijns… - The Journal of …, 2024 - jrheum.org
Objective To conduct a systematic review of the effectiveness and safety of pharmacological
treatments for adult-onset Still disease (AOSD). Methods Six databases, 2 trial registries …

[HTML][HTML] Adult-onset Still's disease: A disease at the crossroad of innate immunity and autoimmunity

S Rao, LSL Tsang, M Zhao, W Shi, Q Lu - Frontiers in medicine, 2022 - frontiersin.org
Adult-onset Still's disease (AOSD) is a rare disease affecting multiple systems and organs
with unknown etiology, and the clinical symptoms are usually described as spiking fever …

Adult‐onset still's disease and treatment results with tocilizumab

S Kır, M Özgen, S Zontul - International Journal of Clinical …, 2021 - Wiley Online Library
Abstract Aims Adult‐onset Still's disease (AOSD) is a rare and non‐familial auto‐
inflammatory disorder. Increased levels of IL‐6 and other pro‐inflammatory cytokines have …

Adult-onset Still's disease: pathogenesis, clinical manifestations and therapeutic advances

A Kontzias, P Efthimiou - Drugs, 2008 - Springer
Adult-onset Still's disease (AOSD) is a rare, systemic inflammatory disease of unknown
aetiology, characterized by daily high spiking fevers, evanescent rash and arthritis. Our …

[HTML][HTML] Efficacy of baricitinib in patients with refractory adult-onset Still's disease

Z Sun, R Li, Y Wang, F Han, W Wei, X Li - Drugs in R&D, 2023 - Springer
Abstract Background and Objective Adult-onset Still's disease (AOSD) is an idiopathic
systemic inflammatory disease of unknown aetiology. Some patients exhibit resistance to …