The role of oxidative stress in the pathogenesis and perpetuation of atrial fibrillation

P Korantzopoulos, TM Kolettis, D Galaris… - International journal of …, 2007 - Elsevier
Atrial fibrillation (AF) is the most common arrhythmia encountered in clinical practice
representing a major health hazard. Owing to relative inefficacy and side effects of classic …

Oxidative stress and atrial fibrillation: an update

P Korantzopoulos, K Letsas, N Fragakis… - Free Radical …, 2018 - Taylor & Francis
Atrial remodelling involves electrophysiological and structural abnormalities that promote
the development and perpetuation of atrial fibrillation. Experimental and clinical data …

Oxidative stress and inflammation in atrial fibrillation: role in pathogenesis and potential as a therapeutic target

DR Van Wagoner - Journal of cardiovascular pharmacology, 2008 - journals.lww.com
Atrial fibrillation (AF) is one of the most prevalent and vexing cardiovascular conditions.
Available treatments for AF based on ion channel blockade are only poorly effective. The …

Oxidant and inflammatory mechanisms and targeted therapy in atrial fibrillation: an update

A Gutierrez, DR Van Wagoner - Journal of cardiovascular …, 2015 - journals.lww.com
Atrial fibrillation (AF) is an important cause of stroke and risk factor for heart failure and
death. Current pharmacologic treatments for AF have limited efficacy, and treatments that …

Oxidative stress in atrial fibrillation: an emerging role of NADPH oxidase

JY Youn, J Zhang, Y Zhang, H Chen, D Liu… - Journal of molecular and …, 2013 - Elsevier
Atrial fibrillation (AF) is the most common cardiac arrhythmia. Patients with AF have up to
seven-fold higher risk of suffering from ischemic stroke. Better understanding of etiologies of …

[HTML][HTML] Reactive oxygen species-targeted therapeutic interventions for atrial fibrillation

AA Sovari, SC Dudley Jr - Frontiers in physiology, 2012 - frontiersin.org
Atrial fibrillation (AF) is the most common arrhythmia that requires medical attention, and its
incidence is increasing. Current ion channel blockade therapies and catheter ablation have …

Electrophysiological remodeling in human atrial fibrillation

DRV Wagoner - Pacing and clinical electrophysiology, 2003 - Wiley Online Library
Atrial fibrillation (AF) is a progressive disease characterized by cumulative
electrophysiological and structural remodeling of the atria. Cellular electrophysiological …

Atrial fibrillation and electrical remodeling: the potential role of inflammation and oxidative stress

P Korantzopoulos, T Kolettis, K Siogas… - Medical Science …, 2003 - medscimonit.com
Atrial fibrillation (AF) represents the most common arrhythmia encountered in clinical
practice. The pathophysiology of AF is complex, but in most cases it may be caused by …

Impact of aldosterone antagonists on the substrate for atrial fibrillation: aldosterone promotes oxidative stress and atrial structural/electrical remodeling

F Mayyas, KH Alzoubi, DR Van Wagoner - International journal of …, 2013 - Elsevier
Atrial fibrillation (AF), the most common cardiac arrhythmia, is an electrocardiographic
description of a condition with multiple and complex underlying mechanisms. Oxidative …

Gene expression profiling of oxidative stress on atrial fibrillation in humans

YH Kim, JH Lee, DS Lim, WJ Shim, YM Ro… - … & molecular medicine, 2003 - nature.com
Atrial Fibrillation (AF) is thought be caused by oxidative stress. Oxidative stress at the
cellular level results from many factors, including exposure to alcohol, medications, cold …