Oxytocin, brain physiology, and functional connectivity: a review of intranasal oxytocin fMRI studies

RAI Bethlehem, J Van Honk, B Auyeung… - …, 2013 - Elsevier
In recent years the neuropeptide oxytocin (OT) has become one of the most studied peptides
of the human neuroendocrine system. Research has shown widespread behavioural effects …

Oxytocin and brain activity in humans: a systematic review and coordinate-based meta-analysis of functional MRI studies

SA Grace, SL Rossell, M Heinrichs… - …, 2018 - Elsevier
Oxytocin (OXT) is a neuropeptide which has a critical role in human social behaviour and
cognition. Research investigating the role of OXT on functional brain changes in humans …

Oxytocin differentially alters resting state functional connectivity between amygdala subregions and emotional control networks: Inverse correlation with depressive …

M Eckstein, S Markett, KM Kendrick, B Ditzen, F Liu… - Neuroimage, 2017 - Elsevier
The hypothalamic neuropeptide oxytocin (OT) has received increasing attention for its role in
modulating social-emotional processes across species. Previous studies on using intranasal …

Advances in the field of intranasal oxytocin research: lessons learned and future directions for clinical research

DS Quintana, A Lischke, S Grace, D Scheele… - Molecular …, 2021 - nature.com
Reports on the modulatory role of the neuropeptide oxytocin on social cognition and
behavior have steadily increased over the last two decades, stimulating considerable …

Oxytocin's effect on resting-state functional connectivity varies by age and sex

NC Ebner, H Chen, E Porges, T Lin, H Fischer… - …, 2016 - Elsevier
The neuropeptide oxytocin plays a role in social cognition and affective processing. The
neural processes underlying these effects are not well understood. Modulation of …

Oxytocin enhances resting-state connectivity between amygdala and medial frontal cortex

CS Sripada, KL Phan, I Labuschagne… - International Journal …, 2013 - academic.oup.com
The neuropeptide oxytocin (OXT) plays an important role in complex socio-affective
behaviours such as affiliation, attachment, stress and anxiety. Previous studies have focused …

Neural substrates underlying the effects of oxytocin: a quantitative meta-analysis of pharmaco-imaging studies

D Wang, X Yan, M Li, Y Ma - Social Cognitive and Affective …, 2017 - academic.oup.com
The hypothalamic peptide oxytocin (OT) is crucial in social adaptation and used to treat
emotional and social deficits. Here, we conducted a systematic, quantitative meta-analysis of …

Oxytocin-augmented psychotherapy: beware of context

R Hurlemann - Neuropsychopharmacology, 2017 - ncbi.nlm.nih.gov
The hypothalamic peptide oxytocin modulates a wide range of social and cognitive functions
in humans and nonhuman primates. As a result, much effort is currently being devoted to …

Kinetics and dose dependency of intranasal oxytocin effects on amygdala reactivity

FB Spengler, J Schultz, D Scheele, M Essel, W Maier… - Biological …, 2017 - Elsevier
Background Current neuroimaging perspectives on a variety of mental disorders emphasize
dysfunction of the amygdala. The neuropeptide oxytocin (OXT), a key mediator in the …

Oxytocin facilitates the sensation of social stress

M Eckstein, D Scheele, K Weber… - Human brain …, 2014 - Wiley Online Library
Essentially all social species experience social stress which can be a catalyst for detriments
in mental and physical health. The neuropeptide oxytocin (OXT) has been shown to produce …