Drug development strategies for the treatment of obesity: how to ensure efficacy, safety, and sustainable weight loss
S Barja-Fernandez, R Leis, FF Casanueva… - Drug Design …, 2014 - Taylor & Francis
The prevalence of obesity has increased worldwide, and approximately 25%–35% of the
adult population is obese in some countries. The excess of body fat is associated with …
adult population is obese in some countries. The excess of body fat is associated with …
Obesity medications in development
CJ Rebello, FL Greenway - Expert opinion on investigational drugs, 2020 - Taylor & Francis
Introduction: Obesity is compounded by a neurobiology that is resistant to weight loss.
Therefore, the development of pharmacotherapies to address the pathology underlying the …
Therefore, the development of pharmacotherapies to address the pathology underlying the …
Pharmacologic treatment options for obesity: current and potential medications
K Fujioka, MW Lee - Nutrition in Clinical Practice, 2007 - Wiley Online Library
Pharmacotherapy has a role in obesity management when combined with diet, physical
activity, and behavior modification. Currently available therapies are safe when used …
activity, and behavior modification. Currently available therapies are safe when used …
Pharmacotherapy for obesity: novel agents and paradigms
Public health initiatives focused on obesity prevention and lifestyle intervention programmes
for patients with obesity have struggled to contain the obesity epidemic to date. In recent …
for patients with obesity have struggled to contain the obesity epidemic to date. In recent …
Anti-obesity drugs: past, present and future
RJ Rodgers, MH Tschöp… - Disease models & …, 2012 - journals.biologists.com
The ideal anti-obesity drug would produce sustained weight loss with minimal side effects.
The mechanisms that regulate energy balance have substantial built-in redundancy, overlap …
The mechanisms that regulate energy balance have substantial built-in redundancy, overlap …
Current pharmacotherapy for obesity: extrapolation of clinical trials data to practice
KM Gadde - Expert opinion on pharmacotherapy, 2014 - Taylor & Francis
Introduction: When used prudently and in combination with lifestyle modification,
pharmacotherapy has an important role in the management of obesity. Areas covered: This …
pharmacotherapy has an important role in the management of obesity. Areas covered: This …
New advances in models and strategies for developing anti-obesity drugs
GW Kim, JE Lin, ES Blomain… - Expert opinion on drug …, 2013 - Taylor & Francis
Introduction: Obesity is a worldwide pandemic. Obesity-related health and economic costs
are staggering. Existing strategies to combat obesity through lifestyle improvements and …
are staggering. Existing strategies to combat obesity through lifestyle improvements and …
Future pharmacotherapy for obesity: new anti-obesity drugs on the horizon
G Srivastava, C Apovian - Current obesity reports, 2018 - Springer
Abstract Purpose of Review Obesity is a global health crisis with detrimental effects on all
organ systems leading to worsening disease state and rising costs of care. Persons with …
organ systems leading to worsening disease state and rising costs of care. Persons with …
Current options for the pharmacotherapy of obesity
I Gouni-Berthold, HK Berthold - Current Pharmaceutical Design, 2019 - ingentaconnect.com
650 millions of adults are obese worldwide-in the US alone, forty percent of the adults are
obese. Although the obesity pandemic is constantly expanding at very high costs for health …
obese. Although the obesity pandemic is constantly expanding at very high costs for health …
New medications for obesity management: changing the landscape of obesity treatment
N Boulghassoul-Pietrzykowska… - Current Opinion in …, 2013 - journals.lww.com
Treating obesity is crucial as it will ultimately result in the prevention of many related chronic
diseases and will decrease morbidity and mortality. Weight loss medications are a valuable …
diseases and will decrease morbidity and mortality. Weight loss medications are a valuable …