Aerosol delivery during mechanical ventilation: from basic techniques to new devices

R Dhand - Journal of aerosol medicine and pulmonary drug …, 2008 - liebertpub.com
Pressurized metered-dose inhalers (pMDIs) and nebulizers are routinely employed for
aerosol delivery in mechanically ventilated patients. A significant proportion of the aerosol …

Modeling and optimization of nebulizers' performance in non-invasive ventilation using different fill volumes: comparative study between vibrating mesh and jet …

H Saeed, AMA Ali, AA Elberry, AS Eldin… - Pulmonary …, 2018 - Elsevier
Backgrounds Substituting nebulisers by another, especially in non-invasive ventilation (NIV),
involves many process-variables, eg nebulizer-type and fill-volume of respirable-dose …

Lung delivery of salbutamol by dry powder inhaler (Turbuhaler) and small volume antistatic metal spacer (Airomir CFC-free MDI plus NebuChamber)

BJ Lipworth, DJ Clark - European Respiratory Journal, 1997 - Eur Respiratory Soc
As a worldwide ban on the use of chlorofluorocarbons (CFCs) in inhaler devices
approaches, considerable attention has been focused on the production of CFC-free …

In vitro evaluation of aerosol bronchodilator delivery during mechanical ventilation: pressure-control vs. volume control ventilation

DR Hess, C Dillman, RM Kacmarek - Intensive care medicine, 2003 - Springer
Objective To determine the effect of inspiratory time and inspiratory flow pattern on albuterol
delivery by aerosol during mechanical ventilation. Design A ventilator was connected to a …

Development of a high-flow nasal cannula and pharmaceutical aerosol combination device

BM Spence, W Longest, X Wei, S Dhapare… - Journal of aerosol …, 2019 - liebertpub.com
Background: Aerosol drug delivery to the lungs is known to be very inefficient during all
forms of noninvasive ventilation, especially when the aerosol is administered simultaneously …

Aerosol delivery through an adult high-flow nasal cannula circuit using low-flow oxygen

YM Madney, M Fathy, AA Elberry, H Rabea… - Respiratory …, 2019 - rc.rcjournal.com
BACKGROUND: There has been a growing trend toward delivering aerosolized medications
using high-flow nasal cannula (HFNC). In some cases, patients who do not require high-flow …

Influence of Inspiratory Flow Pattern and Nebulizer Position on Aerosol Delivery with a Vibrating-Mesh Nebulizer During Invasive Mechanical Ventilation: An in Vitro …

J Dugernier, X Wittebole, J Roeseler… - Journal of aerosol …, 2015 - liebertpub.com
Background: Aerosol delivery during invasive mechanical ventilation (IMV) depends on
nebulizer type, placement of the nebulizer and ventilator settings. The purpose of this study …

Is Combihaler usable for aerosol delivery in single limb non-invasive mechanical ventilation?

HS Harb, AA Elberry, H Rabea, M Fathy… - Journal of Drug Delivery …, 2017 - Elsevier
Combihaler could connect both pressurized-metered-dose-inhaler (pMDI) and nebulizers to
non-invasive-ventilation-circuit (NIV). This can be used to give the patient preliminary …

[HTML][HTML] Aerosol delivery via invasive ventilation: a narrative review

HL Lin, JB Fink, H Ge - Annals of Translational Medicine, 2021 - ncbi.nlm.nih.gov
In comparison with spontaneously breathing non-intubated subjects, intubated,
mechanically ventilated patients encounter various challenges, barriers, and opportunities in …

Comparison of vibrating mesh and jet nebulizers during noninvasive ventilation in acute exacerbation of chronic obstructive pulmonary disease

SN Avdeev, GS Nuralieva, AK Soe… - Journal of Aerosol …, 2021 - liebertpub.com
Background: Advances in aerosol technology have improved drug delivery efficiency during
noninvasive ventilation (NIV). Clinical evaluation of the efficacy of aerosol therapy during …