The MAGhaler (Mundipharma GmbH) is a multidose dry powder inhaler (DPI) containing a
novel formulation of drug and lactose compacted by an isostatic pressing technique (GGU …

Administration of drugs via the airway is increasingly practiced in ICU-and surgical patients.
For this purpose, aerosols may be produced by either jet nebulization or ultrasonic droplet …

High intra-subject variability in lung dose achieved when using aerosol delivery systems
may impact on the efficacy of treatment in clinical practice. While the dose delivered by …

Successful aerosol therapy in mechanically ventilated patients depends on multiple factors.
Among these, position of nebulizer in ventilator circuit and humidification of inhaled gases …

BACKGROUND: The type of aerosol generator and the position in the ventilator circuit are
crucial to determine aerosol delivery during mechanical ventilation. We compared lung …

Inhaled therapy is commonly employed in mechanically ventilated patients with chronic
obstructive pulmonary disease or asthma. The efficacy of inhaled drugs is comparable to …

BACKGROUND: Infants and young children are obligate nose breathers; therefore, a
transnasal route seems the logical delivery method of inhaled aerosols. The efficiency of …

BACKGROUND: This study compared 3 nebulizer technologies for inter-and intradevice
reproducibility, humidification, and fill volume sensitivity during mechanical ventilation: a …

BACKGROUND: Noninvasive ventilation (NIV) is usually applied using bi-level positive
airway pressure devices, and many of these devices use a single-limb patient circuit with an …

The choice of a nebulized system for a patient usually depends on the equipment available.
To date, there is limited guidance on the selection and use of a nebulizer. We have …