Tremendous efforts have been made in building an artificial protocell that could undergo self-
replication and Darwinian evolution. Self-replicating genetic polymers, which serve as major …

Although written 15 years ago, DawkinsÃs sketches astonishingly pre 'gure the results of the
past four years of my work on self-replication. Molecules, natural or synthetic, are able to …

The first non-enzymatic self-replicating systems, as proposed by von Kiedrowski (Angew
Chem Int Ed Engl 25 (10): 932–935, 1986) and Orgel (Nature 327 (6120): 346–347, 1987) …

Among the key characteristics of living systems are their ability to self‐replicate and the fact
that they exist in an open system away from equilibrium. Herein, we show how the outcome …

A simple synthetic autocatalytic replicator is capable of establishing and driving the
propagation of a reaction–diffusion front within a 50 μL syringe. This replicator templates its …

Replicators are the most important objects of evolutionary biology. Their cumulative
evolution lead to the emergence of complex, adaptive systems, like life. All major transitions …

A key characteristic of living systems is the storage and replication of information, and as
such the development of self‐replicating systems capable of heredity is of great importance …

The synthesis of artificial living systems is one of the grand challenges of modern chemistry.
This goal goes beyond simple autocatalysis or self-replication to include the essential …

Abstract Making artificial (“de-novo”) life from completely synthetic molecules is a
challenging endeavour that could help us understand life, detect it, and gain some insight on …

Abstract A``self-replicator''is usually understood to be an object of definite form that promotes
the conversion of materials in its environment into a nearly identical copy of itself. The …