The use of Pd2dba3 with bulky, electron-rich ligands 1 or 2 and LiN (TMS) 2 as the base for
the coupling of amines with aryl halides containing hydroxyl, amide, or enolizable keto …

Herein, we report a Pd (II)-catalyzed β-C (sp3)–H nitrooxylation of ketones and native
amides. The fine-tuned removable aminooxyamide auxiliary enabled β-C (sp3)–H …

Selective C− H bond functionalization enables efficient access to valuable products from
relatively simple precursors and thus remains a longstanding challenge in organic …

Over the years, silver salts have become an integral part of palladium-catalyzed C–H
functionalization. Although most of the research works highlight the role of Ag (I) complexes …

The first amide-directed, palladium-catalyzed, intermolecular, highly selective C− H
aminations with the non-nitrene-based nitrogen source N-fluorobenzenesulfonimide have …

Aliphatic primary amines are a class of chemical feedstock essential to the synthesis of
higher-order nitrogen-containing molecules, commonly found in biologically active …

Conspectus Catalytic reactions that construct carbon–nitrogen bonds are one of central
themes in both synthetic and medicinal chemistry since the obtainable nitrogen-containing …

Here we report a method for the site-selective intermolecular C (sp3)–H amination of
carboxamides by merging transition-metal catalysis and the hydrogen atom transfer strategy …

This Review summarizes the advancements in Pd-catalyzed C (sp3)–H activation via
various redox manifolds, including Pd (0)/Pd (II), Pd (II)/Pd (IV), and Pd (II)/Pd (0). While few …

Reactions that directly install nitrogen into C–H bonds of complex molecules are significant
because of their potential to change the chemical and biological properties of a given …