[HTML][HTML] Pancreatic cancer chemoresistance to gemcitabine
M Amrutkar, IP Gladhaug - Cancers, 2017 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC), commonly referred to as pancreatic cancer,
ranks among the leading causes of cancer-related deaths in the Western world due to …
ranks among the leading causes of cancer-related deaths in the Western world due to …
Gemcitabine: metabolism and molecular mechanisms of action, sensitivity and chemoresistance in pancreatic cancer
L de Sousa Cavalcante, G Monteiro - European journal of pharmacology, 2014 - Elsevier
Gemcitabine is the first-line treatment for pancreatic adenocarcinoma, but is increasingly
used to treat breast, bladder, and non-small cell lung cancers. Despite such broad use …
used to treat breast, bladder, and non-small cell lung cancers. Despite such broad use …
Gemcitabine: a review of chemoresistance in pancreatic cancer
D Sarvepalli, MU Rashid, AU Rahman… - Critical Reviews™ in …, 2019 - dl.begellhouse.com
Pancreatic ductal adenocarcinoma, an exocrine tumor, is the most common type of cancer of
the pancreas and one of the top five most prominent causes of cancer-associated mortality …
the pancreas and one of the top five most prominent causes of cancer-associated mortality …
Overcoming nucleoside analog chemoresistance of pancreatic cancer: a therapeutic challenge
SW Hung, HR Mody, R Govindarajan - Cancer letters, 2012 - Elsevier
Clinical refractoriness to nucleoside analogs (eg, gemcitabine, capecitabine) is a major
scientific problem and is one of the main reasons underlying the extremely poor prognostic …
scientific problem and is one of the main reasons underlying the extremely poor prognostic …
[HTML][HTML] Chemoresistance in pancreatic cancer
S Zeng, M Pöttler, B Lan, R Grützmann… - International journal of …, 2019 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC), generally known as pancreatic cancer (PC),
ranks the fourth leading cause of cancer-related deaths in the western world. While the …
ranks the fourth leading cause of cancer-related deaths in the western world. While the …
Gemcitabine resistance in pancreatic cancer: picking the key players
MP Kim, GE Gallick - Clinical Cancer Research, 2008 - AACR
The diagnosis of pancreatic cancer confers a grim prognosis that has changed little over the
last 30 years. Due to the lack of any efficacious screening or biomarkers for pancreatic …
last 30 years. Due to the lack of any efficacious screening or biomarkers for pancreatic …
Gemcitabine resistance in pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDA) ranks fourth among cancer related deaths. The
disappointing 5-year survival rate of below 5% stems from drug resistance to all known …
disappointing 5-year survival rate of below 5% stems from drug resistance to all known …
Chemoresistance in pancreatic cancer: Emerging concepts
M Gnanamony, CS Gondi - Oncology letters, 2017 - spandidos-publications.com
Pancreatic cancer is one of the most lethal types of cancer in the world. The incidence of
pancreatic cancer increases each year with no significant decrease in mortality. Pancreatic …
pancreatic cancer increases each year with no significant decrease in mortality. Pancreatic …
Barriers and opportunities for gemcitabine in pancreatic cancer therapy
AK Beutel, CJ Halbrook - American Journal of Physiology …, 2023 - journals.physiology.org
Pancreatic ductal adenocarcinoma (PDA) has become one of the leading causes of cancer-
related deaths across the world. A lack of durable responses to standard-of-care …
related deaths across the world. A lack of durable responses to standard-of-care …
Molecular and cellular mechanisms of chemoresistance in pancreatic cancer
A Adamska, O Elaskalani, A Emmanouilidi… - Advances in biological …, 2018 - Elsevier
Abstract Pancreatic Ductal Adenocarcinoma (PDAC) is one of the most chemoresistant
cancers, and current therapies targeting cancer-associated molecular pathways have not …
cancers, and current therapies targeting cancer-associated molecular pathways have not …