HPV-induced oropharyngeal cancer, immune response and response to therapy

HL Vu, AG Sikora, S Fu, J Kao - Cancer letters, 2010 - Elsevier
Approximately 25% of head and neck squamous cell carcinoma (HNSCC) worldwide are
associated with high-risk human papillomaviruses (HPV). HPV-positive HNSCCs have a …

Increased radiosensitivity of HPV-positive head and neck cancers: Molecular basis and therapeutic perspectives

H Mirghani, F Amen, Y Tao, E Deutsch, A Levy - Cancer treatment reviews, 2015 - Elsevier
Human papillomavirus driven head and neck squamous cell carcinoma (HNSCC),
particularly oropharyngeal squamous cell carcinoma (OPSCC), are characterized by a …

Enhanced radiation sensitivity of human papillomavirus-driven head and neck cancer: focus on immunological aspects

M Özcan-Wahlbrink, C Schifflers… - Frontiers in …, 2019 - frontiersin.org
Head and neck squamous cell carcinomas (HNSCC), emerging in the mucosa of the upper
aerodigestive tract, are associated with either the classical risk factors, tobacco and alcohol …

Biological basis for increased sensitivity to radiation therapy in HPV‐positive head and neck cancers

V Bol, V Grégoire - BioMed research international, 2014 - Wiley Online Library
Although development of head and neck squamous cell carcinomas (HNSCCs) is commonly
linked to the consumption of tobacco and alcohol, a link between human papillomavirus …

Immune response during therapy with cisplatin or radiation for human papillomavirus–related head and neck cancer

WC Spanos, P Nowicki, DW Lee… - … –head & neck …, 2009 - jamanetwork.com
Background Human papillomavirus (HPV) is the most identifiable cause of head and neck
squamous cell cancer (HNSCC). Compared with HPV-negative HNSCC, HPV-positive …

Biological features of human papillomavirus-related head and neck cancers contributing to improved response

C Cleary, JE Leeman, DS Higginson, N Katabi… - Clinical Oncology, 2016 - Elsevier
Head and neck squamous cell carcinomas (HNSCC) are the sixth most common malignancy
globally, and an increasing proportion of oropharyngeal HNSCCs are associated with the …

The interplay between HPV and host immunity in head and neck squamous cell carcinoma

AS Andersen, AS Koldjær Sølling… - … journal of cancer, 2014 - Wiley Online Library
Persistent infection with human papillomavirus (HPV) type 16 is a major risk factor for the
development of head and neck squamous cell carcinoma (HNSCC), in particular …

The role of Human papillomavirus in head and neck cancer and the impact on radiotherapy outcome

P Lassen - Radiotherapy and oncology, 2010 - Elsevier
The profound influence of Human papillomavirus (HPV) on the epidemiological pattern and
clinical course of head and neck cancer (HNSCC) has led to a change in the traditional …

Enhanced radiation sensitivity in HPV-positive head and neck cancer

RJ Kimple, MA Smith, GC Blitzer, AD Torres, JA Martin… - Cancer research, 2013 - AACR
Patients with human papillomavirus (HPV+)–associated head and neck cancer (HNC) show
significantly improved survival outcome compared with those with HPV-negative (HPV−) …

New treatment strategies for HPV-positive head and neck cancer

B Kofler, S Laban, CJ Busch, B Lörincz… - European Archives of Oto …, 2014 - Springer
Epidemiological studies show an increasing incidence of human papilloma virus-associated
oropharyngeal cancer. HPV-positive head and neck squamous cell carcinoma (HNSCC) is …