Chronic nonhealing wounds have been heralded as a silent epidemic, causing significant
morbidity and mortality especially in elderly, diabetic, and obese populations. Polymicrobial …

Significance: Culture-independent methods have revealed the diverse and dynamic
bacterial communities that colonize chronic wounds. Only recently have studies begun to …

Wound healing is a highly coordinated and complex process, and there can be devastating
consequences if it is interrupted. It is believed that, in combination with host factors …

Microbial burden of chronic wounds is believed to play an important role in impaired healing
and the development of infection-related complications. However, clinical cultures have little …

Significance: Bacterial burden is believed to play a significant role in impaired wound
healing of chronic wounds and the development of infection-related complications. The …

Objective: To assess the incidence, abundance and species diversity of fungi in chronic
wounds, as well as to describe the associations of major fungi populations. Method …

Chronic wounds are a major complication of diabetes associated with high morbidity and
health care expenditures. To investigate the role of colonizing microbiota in diabetic wound …

The skin microbiota is intimately coupled with cutaneous health and disease. Interactions
between commensal microbiota and the multiple cell types involved in cutaneous wound …

Diabetics chronic wounds are characterized by high levels of oxidative stress (OS) and are
often colonized by biofilm-forming bacteria that severely compromise healing and can result …

Microbes colonizing and/or infecting chronic wounds undoubtedly play a major and
interactive role in impaired healing, especially in amplifying and perpetuating the host innate …