A number of chronic diseases have benefited from both imaging and personalised medicine,
but unfortunately, for patients with chronic obstructive pulmonary disease (COPD), there has …

While the recent development of quantitative imaging methods have led to their increased
use in the diagnosis and management of many chronic diseases, medical imaging still plays …

Computed tomography (CT) is the modality of choice for imaging the thorax and lung
structure. In chronic obstructive pulmonary disease (COPD), it used to recognise the key …

Chronic obstructive pulmonary disease (COPD) is a complex and heterogeneous disease,
and there is a clinical need for validated markers and biomarkers that can contribute to the …

Although the human and societal burden and cost of COPD is staggering, there are few
clinical tools that provide earlier diagnoses or a means to regionally monitor disease in a …

Lung imaging is increasingly being used to diagnose, quantify, and phenotype chronic
obstructive pulmonary disease (COPD). Although spirometry is the gold standard for the …

1. Pellegrino R, Viegi G, Brusasco V, et al. Interpretative strategies for lung function tests. Eur
Respir J 2005; 26: 948–68. 2. Celli BR, MacNee W. Standards for the diagnosis and …

Chronic obstructive pulmonary disease (COPD) is increasingly being recognized as a highly
heterogeneous disorder, composed of varying pathobiology. Accurate detection of COPD …

In a working group of the National Institutes of Health focusing on biomarkers and surrogate
end-points, a biomarker was defined as a “characteristic that is objectively measured and …

Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease characterized
by both small airway and parenchymal abnormalities. There is increasing evidence to …