Beneficial effects of fibroblast growth factor 10 supplementation during in vitro maturation of buffalo cumulus-oocyte complexes

S Du, Y Wang, X Yang, X Liu, K Deng, M Chen, X Yan… - Theriogenology, 2023 - Elsevier
Abstract Fibroblast growth factor 10 (FGF10) is an important regulator of the mammalian
cumulus-oocyte complex that plays a crucial role in oocyte maturation. In this study, we …

Effects of MEK1/2 inhibitor U0126 on FGF10-enhanced buffalo oocyte maturation in vitro

S Du, Y Wang, F Lu, W Zhou - Reproductive Biology, 2024 - Elsevier
Abstract Fibroblast growth factor 10 (FGF10) plays critical roles in oocyte maturation and
embryonic development; however, the specific pathway by which FGF10 promotes in vitro …

Fibroblast growth factor 10 markedly improves in vitro maturation of porcine cumulus‐oocyte complexes

YJ Son, SE Lee, H Hyun, MY Shin… - Molecular …, 2017 - Wiley Online Library
Growth factors synthesized by ovarian somatic cells affect cumulus cell expansion and
oocyte maturation in vitro. Fibroblast growth factor 10 (FGF10), for example, is a known …

Effects of FGF10 on Bovine Oocyte Meiosis Progression, Apoptosis, Embryo Development and Relative Abundance of Developmentally Important Genes In Vitro

RF Pomini Pinto, PK Fontes, B Loureiro… - … in Domestic Animals, 2015 - Wiley Online Library
Contents Fibroblast growth factor (FGF10) acts at the cumulus oocyte complex, increasing
the expression of cumulus cell expansion‐related genes and oocyte competency genes. We …

Fibroblast growth factor 2 regulates cumulus differentiation under the control of the oocyte

RG Barros, PF Lima, ACS Soares, L Sanches… - Journal of Assisted …, 2019 - Springer
Purpose We first assessed regulation of FGF2 expression in cumulus cells by FSH and
oocyte-secreted factors during in vitro maturation (IVM). Then, we tested the hypothesis that …

Bovine in vitro embryo production: the effects of fibroblast growth factor 10 (FGF10)

MN Diógenes, ALS Guimarães, LO Leme… - Journal of assisted …, 2017 - Springer
Purpose In an attempt to improve in vitro embryo production, we investigated the effect of
fibroblast growth factor 10 (FGF10) during in vitro maturation on the developmental capacity …

Supplementation with fibroblast growth factor 7 during in vitro maturation of porcine cumulus-oocyte complexes improves oocyte maturation and early embryonic …

H Zheng, H Choi, D Oh, M Kim, L Cai… - Frontiers in Veterinary …, 2023 - frontiersin.org
In vitro generation of porcine embryos is an indispensable method in the realms of both
agriculture and biomedicine. Nonetheless, the extant procedures encounter substantial …

Effect of basic fibroblast growth factor (FGF2) on cumulus cell expansion, in vitro embryo production and gene expression in buffalo (Bubalus bubalis)

S Kumar, SK Singla, R Manik, P Palta… - Reproductive Biology, 2020 - Elsevier
The present study was undertaken to evaluate the effect of different concentration of FGF2
viz. 5 ng (T1), 10 ng (T2), and 20 ng/mL (T3) on cumulus cell expansion, oocyte maturation …

Bone morphogenetic protein 15 supplementation enhances cumulus expansion, nuclear maturation and progesterone production of in vitro‐matured bovine cumulus …

JC Delgado, TRS Hamilton, CM Mendes… - … in Domestic Animals, 2021 - Wiley Online Library
In vitro embryo production (IVP) efficiency is reduced when compared to in vivo. The basic
knowledge of bovine in vitro oocyte maturation (IVM) mechanisms provides support to …

Exogenous growth differentiation factor 9 in oocyte maturation media enhances subsequent embryo development and fetal viability in mice

CX Yeo, RB Gilchrist, JG Thompson… - Human …, 2008 - academic.oup.com
BACKGROUND Successful oocyte in vitro maturation (IVM) would eliminate the need for
hormonal stimulation used in assisted reproduction techniques. Unfortunately, oocytes …