The role of normothermic extracorporeal perfusion in minimizing ischemia reperfusion injury

T Vogel, JG Brockmann, C Coussios, PJ Friend - Transplantation reviews, 2012 - Elsevier
The primary objective of organ preservation is to deliver a viable graft with minimal risk of
impaired postoperative graft function. In current clinical practice, preservation of transplanted …

Normothermic perfusion: a mini-review

SP Reddy, J Brockmann, PJ Friend - Transplantation, 2009 - journals.lww.com
The quality of organ preservation is critical to the outcome of transplantation: preservation
technology is a limiting factor in the further development in the use of marginal donor …

Perspectives in organ preservation

MHJ Maathuis, HGD Leuvenink, RJ Ploeg - Transplantation, 2007 - journals.lww.com
Maintaining organ viability after donation until transplantation is critically important for
optimal graft function and survival. To date, static cold storage is the most widely used form …

New strategies and concepts in organ preservation

T Hoffmann, T Minor - European Surgical Research, 2015 - karger.com
Organ transplantation is still affected by a notable degree of preservation-associated
ischemia and reperfusion injury, which can seriously hamper early graft function. The …

Machine perfusion or cold storage in organ transplantation: indication, mechanisms, and future perspectives

X Yuan, AJ Theruvath, X Ge… - Transplant …, 2010 - Wiley Online Library
Most organs are currently preserved by cold storage (CS) prior to transplantation. However,
as more so called marginal donor organs are utilized, machine perfusion has regained …

Hypothermic perfusion preservation: the future of organ preservation revisited?

BJ Fuller, CY Lee - Cryobiology, 2007 - Elsevier
Hypothermic perfusion preservation (HPP) was an integral step in the development of early
clinical transplantation programmes, and considerable progress was made in understanding …

Organ preservation: current concepts and new strategies for the next decade

EE Guibert, AY Petrenko, CL Balaban… - Transfusion Medicine …, 2011 - karger.com
Organ transplantation has developed over the past 50 years to reach the sophisticated and
integrated clinical service of today through several advances in science. One of the most …

The future of organ perfusion and re‐conditioning

A Weissenbacher, G Vrakas, D Nasralla… - Transplant …, 2019 - Wiley Online Library
Organ preservation and re‐conditioning using machine perfusion technologies continue to
generate promising results in terms of viability assessment, organ utilization and improved …

Tissue conservation for transplantation

N Krezdorn, S Tasigiorgos, L Wo, M Turk… - Innovative Surgical …, 2017 - degruyter.com
Pathophysiological changes that occur during ischemia and subsequent reperfusion cause
damage to tissues procured for transplantation and also affect long-term allograft function …

Abdominal organ preservation solutions in the age of machine perfusion

P Ramos, P Williams, J Salinas, J Vengohechea… - …, 2023 - journals.lww.com
The past decade has been the foreground for a radical revolution in the field of preservation
in abdominal organ transplantation. Perfusion has increasingly replaced static cold storage …