The emergence and global distribution of the mcr-1 gene for colistin resistance have
become a public concern because of threats to the role of colistin as the last line of defense …

Considering the serious threat to food safety and public health posed by pathogens with
colistin resistance, colistin was banned as a growth promoter in 2017 in China. In recent …

The global dissemination of colistin resistance has received a great deal of attention.
Recently, the plasmid-mediated colistin resistance encoded by mcr genes in Escherichia …

The emergence of the plasmid-mediated colistin resistance gene mcr-1 is threatening the
last-line role of colistin in human medicine. With mcr-1-positive Escherichia coli (E. coli) …

The mcr-1 gene is a plasmid-borne and globally distributed colistin-resistance gene, which
threatens the last-line role of colistin in treatment of infections caused by multi-drug resistant …

Abstract Objectives In November 2015, a plasmid-mediated colistin resistance, MCR-1, was
described in animals, food and humans in China, and it was considered as a potential …

Objectives Colistin is known as the last resort antibiotic to treat the infections caused by multi-
drug resistant (MDR) foodborne pathogens. The emergence and widespread dissemination …

Colistin is the last line of defense for the treatment of multidrug-resistant gram-negative
bacterial infections. However, colistin resistance is gradually increasing worldwide, with …

Background mcr-1-positive Escherichia coli has emerged as a significant threat to human
health, veterinary health, and food safety in recent years. After the prohibition of colistin as a …

The objective of this study was to determine the minimal inhibitory concentration of colistin
for Escherichia coli from food animals and the possible underlying colistin resistance …