Background Ovarian cancer is a common malignancy in the female reproductive system with
a high mortality rate. The most important reason is multidrug resistance (MDR) of cancer …

Purpose The aim of this study was to test the ability of paclitaxel-loaded poly
(butylcyanoacrylate)(PBCA) nanoparticles to overcome multidrug resistance (MDR) in …

The biggest challenge for the treatment of multidrug resistance cancer is to deliver high
concentration of anticancer drugs specifically to cancer cells for longer period of time …

Introductions Ovarian cancer is a stubborn malignancy of gynecological system with a high
mortality rate. Docetaxel (DTX), the second-generation of anti-tumor drug Taxane, has …

The therapeutic potential of mixed micelles, made of PEG-PE and vitamin E co-loaded with
curcumin and paclitaxel, was investigated against SK-OV-3 human ovarian adenocarcinoma …

Nanoparticle drug delivery system (NDDS) is quite different from the widely studied
traditional chemotherapy which suffers from drug resistance and side effect. NDDS offers the …

Paclitaxel (PTX) is frequently suffered from multidrug resistance (MDR), resulting in lower
chemotherapeutic efficacy and even chemotherapy failure. To combine the P-glycolprotein …

Development of multidrug resistance (MDR) against a variety of conventional and novel
chemotherapeutic agents is a significant challenge in effective cancer therapy. Over the last …

Development of multidrug resistance against chemotherapeutic drugs is one of the major
obstacles to successful cancer therapy in the clinic. Thus far, amphiphilic polymeric micelles …

Synergetic treatments that combine chemotherapy with photothermal/photodynamic therapy
have been developed as promising new strategies for cancer therapy, especially for drug …