An efficient computing strategy for estimating variance and covariance components between
and within random effects by Restricted Maximum Likelihood is described. It pertains to data …

The mechanism by which genetic variability is maintained in natural populations for
quantitative characters is not well understood. Many observations show that there is a …

The well-known simplex model is extended to a model that may be used for the genetic and
environmental analysis of covariance structures. This “double” simplex structure can be …

Two recent articles in this journal have dis-cussed the relationship between quantitative
genetic models and evolutionarily stable strategy (ESS) models of the evolution of …

Maximum likelihood methods of estimating genetic variances and covariances in balanced
and unbalanced designs are discussed. Methodological modifications required when …

The multivariate normal parameterization of the polygenic model (Lange et al., 1976)
provides a great deal of flexibility for analyzing quantitative data on pedigrees. The …

A quantitative genetic model relates the genotypic value of an individual to the alleles at the
loci that contribute to the variation in a population in terms of additive, dominance, and …

A model of the quantitative genetics of phenotypically plastic characters is developed. When
genotype-environment interaction is present, and the allelic effects contributing to any two …

We propose a new method for approximate Bayesian statistical inference on the basis of
summary statistics. The method is suited to complex problems that arise in population …

We present a new method of quantitative-trait linkage analysis that combines the simplicity
and robustness of regression-based methods and the generality and greater power of …