Salidroside-can it be a multifunctional drug?

SKJ Magani, SD Mupparthi, BP Gollapalli… - Current Drug …, 2020 - ingentaconnect.com
Background: Salidroside is a glucoside of tyrosol found mostly in the roots of Rhodiola spp. It
exhibits diverse biological and pharmacological properties. In the last decade, enormous …

Salidroside: A review of its recent advances in synthetic pathways and pharmacological properties

X Zhang, L Xie, J Long, Q Xie, Y Zheng, K Liu… - Chemico-Biological …, 2021 - Elsevier
Salidroside has been identified as one of the most potent compounds isolated from various
Rhodiola plants, which have been used for a long time as adaptogens in traditional Chinese …

The therapeutic effects and mechanisms of salidroside on cardiovascular and metabolic diseases: an updated review

CC Zhao, XY Wu, H Yi, R Chen… - Chemistry & …, 2021 - Wiley Online Library
The increasing incidence of metabolic and cardiovascular diseases has severely affected
global human health and life safety. In recent years, some effective drugs with remarkable …

Advances in research on anticancer properties of salidroside

A Sun, XL Ju - Chinese journal of integrative medicine, 2021 - Springer
Salidroside is a phenolic secondary metabolite present in plants of the genus Rhodiola, and
studies investigating its extensive pharmacological activities and mechanisms have recently …

Synthesis, biological activity of salidroside and its analogues

Y Guo, Y Zhao, C Zheng, Y Meng… - Chemical and …, 2010 - jstage.jst.go.jp
Salidroside is a phenylpropanoid glycoside isolated from Rhodiola rosea L., a traditional
Chinese medicinal plant, and has displayed a broad spectrum of pharmacological …

Pharmacokinetics, tissue distribution, and excretion of salidroside in rats

Y Zhang, L Li, L Lin, J Liu, Z Zhang, D Xu… - Planta …, 2013 - thieme-connect.com
The present study investigated the pharmacokinetics, excretion, and tissue distribution of
salidroside, a main active constituent in the roots of Rhodiola species. The plasma …

HPLC analysis, semi-preparative HPLC preparation and identification of three impurities in salidroside bulk drug

Y Peng, J Luo, Q Lu, X Chen, Y Xie, L Chen… - … of pharmaceutical and …, 2009 - Elsevier
Salidroside is a bioactive compound mainly distributed in Rhodiola L.(Crassulaceae). It has
been widely used in Chinese traditional medicine. In this paper, three impurities were found …

Development and validation of a liquid chromatographic/electrospray ionization mass spectrometric method for the determination of salidroside in rat plasma …

S Yu, L Liu, T Wen, Y Liu, D Wang, Y He… - … of Chromatography B, 2008 - Elsevier
A sensitive and specific liquid chromatography–electrospray ionization-mass spectrometry
(LC–ESI-MS) method has been developed and validated for the identification and …

The Metabolism of Salidroside to Its Aglycone p-Tyrosol in Rats following the Administration of Salidroside

N Guo, M Zhu, X Han, D Sui, Y Wang, Q Yang - PLoS One, 2014 - journals.plos.org
Salidroside is one of the major phenolic glycosides in Rhodiola, which has been reported to
possess various biological activities. In the present study the in vivo deglycosylation …

Simultaneous Determination of Salidroside and Its Aglycone Metabolite p-Tyrosol in Rat Plasma by Liquid Chromatography-Tandem Mass Spectrometry

N Guo, Z Hu, X Fan, J Zheng, D Zhang, T Xu, T Yu… - Molecules, 2012 - mdpi.com
Salidroside and its aglycone p-tyrosol are two major phenols in the genus Rhodiola and
have been confirmed to possess various pharmacological properties. In our present study, p …