Salidroside improves glucose homeostasis in obese mice by repressing inflammation in white adipose tissues and improving leptin sensitivity in hypothalamus

M Wang, L Luo, L Yao, C Wang, K Jiang, X Liu, M Xu… - Scientific Reports, 2016 - nature.com
Salidroside is a functionally versatile natural compound from the perennial flowering plant
Rhodiola rosea L. Here, we examined obese mice treated with salidroside at the dosage of …

Beneficial Effects of Rhodiola and Salidroside in Diabetes: Potential Role of AMP-Activated Protein Kinase

T Zheng, F Bian, L Chen, Q Wang, S Jin - Molecular Diagnosis & Therapy, 2019 - Springer
Diabetes mellitus represents a chronic metabolic disorder characterized by impaired lipid
homeostasis and carbohydrate metabolism, gradually leading to persistent hyperglycemia …

[HTML][HTML] Effects of salidroside on glioma formation and growth inhibition together with improvement of tumor microenvironment

Y Zhang, Y Yao, H Wang, Y Guo… - Chinese Journal of …, 2013 - ncbi.nlm.nih.gov
Objective To test the effects of salidroside on formation and growth of glioma together with
tumor microenvironment. Methods Salidroside extracted from Rhodiola rosea was purified …

Salidroside inhibits migration and invasion of human fibrosarcoma HT1080 cells

C Sun, Z Wang, Q Zheng, H Zhang - Phytomedicine, 2012 - Elsevier
Oxidative stress plays an important role in tumorigenesis and metastasis. Salidroside, a
phenylpropanoid glycoside isolated from Rhodiola rosea L., shows potent antioxidant …

Salidroside induces apoptosis and autophagy in human colorectal cancer cells through inhibition of PI3K/Akt/mTOR pathway

XJ Fan, Y Wang, L Wang, M Zhu - Oncology Reports, 2016 - spandidos-publications.com
The role of salidroside in colon cancer remains unknown. Here we show that salidroside, a
phenylpropanoid glycoside extracted from Rhodiola rosea, exhibited potent anti-proliferative …

Protective Effect of Salidroside from Rhodiolae Radix on Diabetes-Induced Oxidative Stress in Mice

F Li, H Tang, F Xiao, J Gong, Y Peng, X Meng - Molecules, 2011 - mdpi.com
It has been confirmed that diabetes mellitus (DM) carries increased oxidative stress. This
study evaluated the effects of salidroside from Rhodiolae Radix on diabetes-induced …

[HTML][HTML] Salvianolic acid A & B: Potential cytotoxic polyphenols in battle against cancer via targeting multiple signaling pathways

T Qin, A Rasul, A Sarfraz, I Sarfraz… - … journal of biological …, 2019 - ncbi.nlm.nih.gov
Nature has generously offered life-saving therapies to mankind by providing evolutionarily
optimized drug-like entities in the form of natural products. These splendid gifts of nature …

[PDF][PDF] The cardiovascular effects of salidroside in the Goto-Kakizaki diabetic rat model

A Alameddine, Z Fajloun, J Bourreau… - J Physiol …, 2015 - jpp.krakow.pl
Many factors, including hyperglycemia, hypertension, obesity, dyslipidemia, and a sedentary
lifestyle, contribute to a high prevalence of cardiovascular disease. Specific vascular …

Salvianolic acid B slows the progression of breast cancer cell growth via enhancement of apoptosis and reduction of oxidative stress, inflammation, and angiogenesis

MA Katary, R Abdelsayed, A Alhashim… - International journal of …, 2019 - mdpi.com
Breast cancer is the current leading cause of cancer death in females worldwide. Although
current chemotherapeutic drugs effectively reduce the progression of breast cancer, most of …

Sorbinil, an aldose reductase inhibitor, in fighting against diabetic complications

Q Huang, Q Liu, D Ouyang - Medicinal Chemistry, 2019 - ingentaconnect.com
Background: Aldose reductase (AR) is involved in the pathogenesis of diabetes, which is
one of the major threats to global public health. Objective: In this review article, we have …