The involvement and therapy target of immune cells after ischemic stroke

Z Jian, R Liu, X Zhu, D Smerin, Y Zhong, L Gu… - Frontiers in …, 2019 - frontiersin.org
After ischemic stroke, the integrity of the blood-brain barrier is compromised. Peripheral
immune cells, including neutrophils, T cells, B cells, dendritic cells, and macrophages …

The translational potential of microglia and monocyte-derived macrophages in ischemic stroke

EE Wicks, KR Ran, JE Kim, R Xu, RP Lee… - Frontiers in …, 2022 - frontiersin.org
The immune response to ischemic stroke is an area of study that is at the forefront of stroke
research and presents promising new avenues for treatment development. Upon cerebral …

The immune response of T cells and therapeutic targets related to regulating the levels of T helper cells after ischaemic stroke

TY Lei, YZ Ye, XQ Zhu, D Smerin, LJ Gu… - Journal of …, 2021 - Springer
Through considerable effort in research and clinical studies, the immune system has been
identified as a participant in the onset and progression of brain injury after ischaemic stroke …

Monocyte‐related cytokines/chemokines in cerebral ischemic stroke

M Bai, R Sun, B Cao, J Feng… - CNS Neuroscience & …, 2023 - Wiley Online Library
Aims Ischemic stroke is one of the leading causes of death worldwide and the most common
cause of disability in Western countries. Multiple mechanisms contribute to the development …

Macrophage and monocyte subsets in response to ischemic stroke

N Blank‐Stein, E Mass - European Journal of Immunology, 2023 - Wiley Online Library
Ischemic stroke is a leading cause of disability and mortality. Despite extensive efforts in
stroke research, the only pharmacological treatment currently available is arterial …

Immune cells after ischemic stroke onset: roles, migration, and target intervention

L Ao, YY Yan, L Zhou, C Li, WT Li, W Fang… - Journal of Molecular …, 2018 - Springer
Ischemic stroke is one of the leading health issues and the major cause of permanent
disability in adults worldwide. Energy depletion and hypoxia occurring after ischemic stroke …

Glial cells: role of the immune response in ischemic stroke

S Xu, J Lu, A Shao, JH Zhang, J Zhang - Frontiers in immunology, 2020 - frontiersin.org
Ischemic stroke, which accounts for 75–80% of all strokes, is the predominant cause of
morbidity and mortality worldwide. The post-stroke immune response has recently emerged …

Inflammatory mechanisms in ischemic stroke: therapeutic approaches

SE Lakhan, A Kirchgessner, M Hofer - Journal of translational medicine, 2009 - Springer
Acute ischemic stroke is the third leading cause of death in industrialized countries and the
most frequent cause of permanent disability in adults worldwide. Despite advances in the …

[HTML][HTML] The local and peripheral immune responses to stroke: implications for therapeutic development

KA Zera, MS Buckwalter - Neurotherapeutics, 2020 - Elsevier
The immune response to stroke is an exciting target for future stroke therapies. Stroke is a
leading cause of morbidity and mortality worldwide, and clot removal (mechanical or …

Inflammation as therapeutic objective in stroke

J Jordán, T Segura, D Brea… - Current …, 2008 - ingentaconnect.com
Ischemic stroke is the most frequent cause of persistent neurologic disability in modern
Western societies. Albeit it is still not clear whether inflammation is merely an …