Serum HE4 as a useful biomarker in discriminating ovarian cancer from benign pelvic disease

H Zheng, Y Gao - International Journal of Gynecologic Cancer, 2012 - ijgc.bmj.com
Objective To evaluate the role of the novel tumor marker human epididymal secretory
protein E4 (HE4) in discriminating ovarian cancer from benign pelvic disease in patients with …

Analysis of serum HE4 levels in various histologic subtypes of epithelial ovarian cancer and other malignant tumors

A Blackman, J Mitchell, R Rowswell-Turner… - Tumor …, 2021 - content.iospress.com
BACKGROUND: The measurement of serum HE4 levels has emerged as a sensitive and
specific biomarker for epithelial ovarian cancers (EOCs). However, serum levels in women …

Prognostic value of HE4 in patients with ovarian cancer

C Yuan, R Li, S Yan, B Kong - Clinical Chemistry and Laboratory …, 2018 - degruyter.com
Background There is no consensus in the medical community about the prognostic role of
preoperative serum levels of human epididymis protein 4 (HE4) in ovarian cancer (OC). The …

Does HE4 have a role as biomarker in the recurrence of ovarian cancer?

F Plotti, S Capriglione, C Terranova, R Montera… - Tumor Biology, 2012 - Springer
Abstract Human epididymis protein 4 (HE4) was recently approved by the Food and Drug
Administration to monitor recurrence or progressive disease in epithelial ovarian cancer in …

HE4 as a predictor of adjuvant chemotherapy resistance and survival in patients with epithelial ovarian cancer

M Aarenstrup Karlsen, C Høgdall, L Nedergaard… - Apmis, 2016 - Wiley Online Library
The aim of this study was to investigate the value of serum human epididymis protein 4
(HE4) and HE 4 tissue protein expression to predict tumor resistance to adjuvant …

Diagnostic and prognostic role of HE4 expression in multiple carcinomas: A protocol for systematic review and meta-analysis

C Kumarasamy, MR Madhav, S Sabarimurugan… - Medicine, 2019 - journals.lww.com
Background: Human epididymis protein 4 (HE4) protein has garnered a great degree of
interest as a complementary biomarker to carbohydrate antigen 125 (CA125), or even as an …

Evaluation of HE4 as an extrabiomarker to CA125 to improve detection of ovarian carcinoma: is it time for a step forward?

AZ Azzam, DI Hashad, NAF Kamel - Archives of gynecology and obstetrics, 2013 - Springer
Purpose To evaluate human epididymis protein 4 (HE4) as an extrabiomarker to cancer
antigen 125 (CA125) to improve the detection of ovarian carcinoma. Methods Sixty patients …

Prognostic significance of Ki67 during neoadjuvant chemotherapy in primary unresectable ovarian cancer

R Kaya, H Takanashi, A Nakajima… - Journal of Obstetrics …, 2021 - Wiley Online Library
Aim The purpose of this study was to investigate whether the Ki67 values were associated
with survival for predicting prognosis in patients with advanced ovarian cancer receiving …

[引用][C] HE4 and CA125 combined for the improved management ovarian cancer

WJ Allard, RG Moore - Oncologie, 2009

HE4 and CA125 serum biomarker monitoring in women with epithelial ovarian cancer

A Samborski, MC Miller, A Blackman… - Tumor …, 2022 - content.iospress.com
BACKGROUND: CA125 is the gold standard serum biomarker for monitoring patients with
epithelial ovarian cancer (EOC). Human epididymal protein 4 (HE4) is a novel serum …