[HTML][HTML] Diagnostic performance of the biomarkers HE4 and CA125 in type I and type II epithelial ovarian cancer

B Kristjansdottir, K Levan, K Partheen, K Sundfeldt - Gynecologic oncology, 2013 - Elsevier
Objective To evaluate the diagnostic performance of HE4 and CA125 in patients presenting
with suspicious malignant ovarian cysts. We especially wanted to investigate the levels of …

Diagnostic biomarkers in ovarian cancer: advances beyond CA125 and HE4

A Ghose, L McCann, S Makker… - … in medical oncology, 2024 - journals.sagepub.com
Ovarian cancer (OC) is the most lethal gynaecologic malignancy, attributed to its insidious
growth, non-specific symptoms and late presentation. Unfortunately, current screening …

Validation of the KELIM score as a predictor of response to neoadjuvant treatment in patients with advanced high grade serous ovarian cancer

S Piedimonte, R Kim, MQ Bernardini, EG Atenafu… - Gynecologic …, 2022 - Elsevier
Objective The objective of this study is to externally validate the KELIM (rate of elimination of
CA-125 elimation) score in patients with high grade serous ovarian cancer (HGSC) …

Role of human epididymis protein 4 (HE4) in detecting recurrence in CA125 negative ovarian cancer patients

F Plotti, F Guzzo, T Schirò, C Terranova… - International Journal of …, 2019 - ijgc.bmj.com
Objective There are no current guidelines regarding evaluation of patients with normal
CA125 at initial diagnosis during routine surveillance after completion of treatment. Thus, the …

HE4 combined with MDCT imaging is a good marker in the evaluation of disease extension in advanced epithelial ovarian carcinoma

C Midulla, L Manganaro, F Longo, V Viggiani, L Frati… - Tumor Biology, 2012 - Springer
The purpose of the study was to evaluate the expression of the biomarkers CA125 and HE4
combined with imaging, in patients with advanced epithelial ovarian cancer (EOC). Forty-six …

[HTML][HTML] HE4 and eIF3a expression correlates with surgical outcome and overall survival in ovarian cancer patients with secondary cytoreduction

CH Luo, M Zhao, XY Chen, S Shahabi, W Qiang… - Journal of …, 2018 - ncbi.nlm.nih.gov
For recurrent ovarian cancer (ROC), secondary cytoreductive surgery (SCS) is
recommended as one optional treatment. However, little is known about the expression and …

Correlation of serum HE4 with tumor size and myometrial invasion in endometrial cancer

E Kalogera, N Scholler, C Powless, A Weaver… - Gynecologic …, 2012 - Elsevier
OBJECTIVE: To evaluate the utility of serum (HE4) as a marker for high risk disease in
patients with endometrial cancer (EC). METHODS: Preoperative serum HE4 levels were …

Serum HE4 predicts progestin treatment response in endometrial cancer and atypical hyperplasia: A prognostic study

CE Barr, JC Sergeant, HJ Agnew… - … Journal of Obstetrics …, 2023 - Wiley Online Library
Objective To investigate serum human epididymis‐4 (HE4) as a predictive biomarker of
intrauterine progestin response in endometrial cancer and atypical endometrial hyperplasia …

[PDF][PDF] Human epididymal protein 4 (HE4) is a novel biomarker and a promising prognostic factor in ovarian cancer patients.

A Chudecka-Głaz, I Rzepka-Górska… - Eur. J. Gynaec …, 2012 - article.imrpress.com
Purpose of investigation: The aim of this work was to compare serum concentrations of HE4
in patients with benign and malignant epithelial tumors and to determine the association of …

The Importance of CA125 Normalization During Neoadjuvant Chemotherapy Followed by Planned Delayed Surgical Debulking in Patients With Epithelial Ovarian …

T Le, W Faught, L Hopkins… - Journal of Obstetrics and …, 2008 - Elsevier
Objectives To examine the prognostic significance, in patients with ovarian cancer, of
normalization of CA125 levels in serum during neoadjuvant chemotherapy treatment …