Rapid and sensitive detection of optical signals from biological materials has been very
useful in studies of cell physiology and biochemistry. A rapid-scanning spectrophotometer is …

A flexible approach is described to acquire, store, retrieve, and manipulate the large volume
of data provided by a rapid-scanning spectrophotometer designed for biological …

A single-beam recording spectrophotometer capable of measuring absorption and first-
derivative spectra on dense, light-scattering samples at low temperature can be constructed …

The single specimen derivative (SSD) method provides an absolute absorption spectrum of
a substance in the absence of a suitable reference. Both a reference and a measuring …

A mechanical/opto-electronic method for performing reflection spectrophotometry with
advantages of at least 50% in size, mobility, and price over previous, monochromator-based …

The development of noninvasive optical studies necessitates an understanding of the
biological parameters which affect light propagation in soft tissues. In the present report, we …

We have developed an optical system based on visible light spectroscopy for the continuous
study of changes in the redox states of mitochondrial cytochromes in intact mammalian cells …

A special dual-wavelength instrument employing interference filters, together with a high-
intensity excitation and sensitive readout fluorometer, has been constructed for the …

▪ Abstract The interaction of light within tissue has been used to recognize disease since the
mid-1800s. The recent developments of small light sources, detectors, and fiber optic probes …

Optical spectroscopy is the simplest technique for quantitative determination of hemoglobin,
myoglobin, and other mitochondrial enzymes. This technique, however, is restricted to …