Should we evaluate and treat sperm DNA fragmentation?

A Agarwal, CL Cho, SC Esteves - Current Opinion in Obstetrics …, 2016 - journals.lww.com
Sperm DNA fragmentation tests provide clinically relevant information for natural conception
and artificial reproduction independent of those derived from conventional semen …

Sperm DNA fragmentation testing: Summary evidence and clinical practice recommendations

SC Esteves, A Zini, RM Coward, DP Evenson… - Andrologia, 2021 - Wiley Online Library
We herein summarise the evidence concerning the impact of sperm DNA fragmentation in
various clinical infertility scenarios and the advances on sperm DNA fragmentation tests …

[HTML][HTML] Human sperm DNA fragmentation and its correlation with conventional semen parameters

E Evgeni, K Charalabopoulos… - Journal of reproduction …, 2014 - ncbi.nlm.nih.gov
Background The initial step in the diagnostic investigation of male infertility has been
traditionally based on the conventional seminal profile. However, there are significant …

Sperm DNA fragmentation: consequences for reproduction

L Simon, B Emery, DT Carrell - Genetic Damage in Human Spermatozoa, 2019 - Springer
DNA fragmentation, or the accumulation of single-and double-strand DNA breaks, is a
common property of sperm, and an increase in the level of sperm DNA fragmentation is …

[HTML][HTML] Should sperm DNA fragmentation testing be included in the male infertility work-up?

SEM Lewis - Reproductive biomedicine online, 2015 - Elsevier
Should sperm DNA fragmentation testing be included in the male infertility work-up? -
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[HTML][HTML] Measuring sperm DNA fragmentation and clinical outcomes of medically assisted reproduction: a systematic review and meta-analysis

M Cissen, M Wely, I Scholten, S Mansell, JP Bruin… - PloS one, 2016 - journals.plos.org
Sperm DNA fragmentation has been associated with reduced fertilization rates, embryo
quality, pregnancy rates and increased miscarriage rates. Various methods exist to test …

Sperm DNA fragmentation: threshold value in male fertility

M Sergerie, G Laforest, L Bujan… - Human …, 2005 - academic.oup.com
BACKGROUND: The extent of sperm DNA fragmentation, which can be measured by the
TUNEL assay, is one of the determinants of male fertility. However, the clinical application of …

Meta-analysis of sperm DNA fragmentation using the sperm chromatin structure assay

D Evenson, R Wixon - Reproductive biomedicine online, 2006 - Elsevier
Meta-analyses were conducted to investigate the relationship of sperm DNA fragmentation
on pregnancy outcome using in-vivo fertilization, IUI, routine IVF and ICSI. Couples with no …

[HTML][HTML] Sperm DNA fragmentation in reproductive medicine: a review

AT Alahmar, R Singh, A Palani - Journal of human reproductive …, 2022 - journals.lww.com
Approximately 15% of the world's couples suffer from infertility during their reproductive
period of which the male factor is responsible for 50% of cases. Male factor infertility is …

[HTML][HTML] Sperm deoxyribonucleic acid fragmentation as assessed by the sperm chromatin dispersion test in assisted reproductive technology programs: results of a …

JFV de la Calle, A Muller, M Walschaerts, JL Clavere… - Fertility and …, 2008 - Elsevier
OBJECTIVE: To assess the value of sperm DNA fragmentation, measured by the sperm
chromatin dispersion (SCD) test, in predicting fertilization rate, embryo quality, and …