Tackling the recurrence of Clostridium difficile infection

N Petrosillo - Médecine Et Maladies Infectieuses, 2018 - Elsevier
The pathogenesis of recurrent Clostridium difficile infection (CDI) is still poorly understood.
The risk of recurrence is approximately 20% after an initial CDI episode and dramatically …

Derivation and Validation of a Clostridium difficile Infection Recurrence Prediction Rule in a National Cohort of Veterans

KR Reveles, EM Mortensen, JM Koeller… - … : The Journal of …, 2018 - Wiley Online Library
Study Objective Prior studies have identified risk factors for recurrent Clostridium difficile
infection (CDI), but few studies have integrated these factors into a clinical prediction rule …

Recurrent Clostridium difficile infection: from colonization to cure

K Shields, RV Araujo-Castillo, TG Theethira… - Anaerobe, 2015 - Elsevier
Clostridium difficile infection (CDI) is increasingly prevalent, dangerous and challenging to
prevent and manage. Despite intense national and international attention the incidence of …

Prospective derivation and validation of a clinical prediction rule for recurrent Clostridium difficile infection

MY Hu, K Katchar, L Kyne, S Maroo, S Tummala… - Gastroenterology, 2009 - Elsevier
BACKGROUND & AIMS: Prevention of recurrent Clostridium difficile infection (CDI) is a
substantial therapeutic challenge. A previous prospective study of 63 patients with CDI …

[HTML][HTML] Clostridium difficile–from colonization to infection

H Schaeffler, A Breitrueck - Frontiers in microbiology, 2018 - frontiersin.org
Clostridium difficile is the most frequent cause of nosocomial antibiotic-associated diarrhea.
The incidence of C. difficile infection (CDI) has been rising worldwide with subsequent …

[HTML][HTML] Microbiologic factors affecting Clostridium difficile recurrence

CH Chilton, DS Pickering, J Freeman - Clinical Microbiology and Infection, 2018 - Elsevier
Abstract Background Recurrent Clostridium difficile infection (rCDI) places a huge economic
and practical burden on healthcare facilities. Furthermore, rCDI may affect quality of life …

Risk factors for recurrent Clostridium difficile infection: a systematic review and meta-analysis

A Deshpande, V Pasupuleti, P Thota, C Pant… - infection control & …, 2015 - cambridge.org
OBJECTIVEAn estimated 20–30% of patients with primary Clostridium difficile infection
(CDI) develop recurrent CDI (rCDI) within 2 weeks of completion of therapy. While the actual …

Recent Progress for the Effective Prevention and Treatment of Recurrent Clostridium difficile Infection

I Ramsay, NM Brown, DA Enoch - … Diseases: Research and …, 2018 - journals.sagepub.com
Recurrence occurs in approximately 25% of all cases of Clostridium difficile infection (CDI)
and poses a unique clinical challenge. Traditionally, treatment options of CDI have been …

Novel therapies and preventative strategies for primary and recurrent Clostridium difficile infections

MG Dieterle, K Rao, VB Young - … of the New York Academy of …, 2019 - Wiley Online Library
Clostridium difficile is the leading infectious cause of antibiotic‐associated diarrhea and
colitis. C. difficile infection (CDI) places a heavy burden on the healthcare system, with …

Antimicrobial Resistance and Reduced Susceptibility in Clostridium difficile: Potential Consequences for Induction, Treatment, and Recurrence of C. difficile Infection

SD Baines, MH Wilcox - Antibiotics, 2015 - mdpi.com
Clostridium difficile infection (CDI) remains a substantial burden on healthcare systems and
is likely to remain so given our reliance on antimicrobial therapies to treat bacterial …